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Clinical trial condition

alpha 1-Antitrypsin Deficiency

Explore clinical trials studying alpha 1-Antitrypsin Deficiency. Study availability and eligibility vary by location and protocol.

100 public trials 19 recruiting studies
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alpha 1-Antitrypsin Deficiency trial results

Completed

Alpha-1 Foundation Research Registry

NCT00499941

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Medical University of South Carolina. Division of Pulmonary and Critical Care Medicine Charleston, South Carolina, United States
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Completed

Efficacy/Safety of HA Inhalation Solution for Hereditary Emphysema in Patients With Alpha-1 Antitrypsin Deficiency

NCT03114020

Conditions
Alpha 1-Antitrypsin Deficiency, Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +13 more
Locations
  • University of Miami Hospital Miami, Florida, United States
  • Pulmonary Health Physicians, PC Fayetteville, New York, United States
  • Medical University of South Carolina Charleston, South Carolina, United States
  • University of Texas Health Science Center Tyler, Texas, United States
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Completed

Phase II, Safety and Efficacy Study of Kamada-alpha-1-antitrypsin (AAT) for Inhalation"

NCT02001688

Conditions
Alpha-1 Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • University of Florida, Pulmonary, Critical Care & Sleep Medicine Gainesville, Florida, United States
  • The University of Texas Health Science Center at Tyler Center for Clinical Research Tyler, Texas, United States
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Completed

International Study Evaluating the Safety and Efficacy of Inhaled, Human, Alpha-1 Antitrypsin (AAT) in Alpha-1 Antitrypsin Deficient Patients With Emphysema

NCT01217671

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Emphysema, +8 more
Locations
  • Inspiration Research Limited Toronto, Canada
  • Seymour Health Centre Vancouver, Canada
  • Gentofte Hospital Hellerup, Denmark
  • Universitätsklinikum des Saarlandes Homburg/Saar, Germany
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Completed

Alpha-1 Carrier Genomics Study

NCT02810327

Conditions
Alpha-1 Antitrypsin Deficiency, Behavior, COPD, +16 more
Locations
  • Medical University of South Carolina. Division of Pulmonary and Critical Care Medicine Charleston, South Carolina, United States
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Completed

Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency

NCT01054339

Conditions
Alpha-1 Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • National Jewish Health Denver, Colorado, United States
  • University of Massachusetts Medical Center Worcester, Massachusetts, United States
  • Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States
  • Beaumont Hospital Dublin, Ireland
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