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Clinical trial condition

alpha 1-Antitrypsin Deficiency

Explore clinical trials studying alpha 1-Antitrypsin Deficiency. Study availability and eligibility vary by location and protocol.

100 public trials 19 recruiting studies
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alpha 1-Antitrypsin Deficiency trial results

Completed

Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency

NCT03679598

Conditions
Alpha-1 Antitrypsin Deficiency (AATD), Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +15 more
Locations
  • The University of Alabama at Birmingham Lung Health Center Birmingham, Alabama, United States
  • UCLA Los Angeles, California, United States
  • National Jewish Health Denver, Colorado, United States
  • Columbia University New York, United States
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Completed

A Phase 1, First-in-human Study of VX-668

NCT05727800

Conditions
Alpha-1 Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Celerion - Tempe Tempe, Arizona, United States
  • University of Florida Gainesville, Florida, United States
  • Central Florida Pulmonary Group, P.A. Orlando, Florida, United States
  • ICON Lenexa Lenexa, Kansas, United States
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Completed

A Phase 1, First-in-human Study of VX-634

NCT05579431

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Celerion - Tempe Tempe, Arizona, United States
  • University of Florida Gainesville, Florida, United States
  • Central Florida Pulmonary Group, P.A. Orlando, Florida, United States
  • ICON Lenexa Lenexa, Kansas, United States
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Completed

α1-antitrypsin (AAT) Levels and Functions in Allogeneic Bone Marrow Transplantation and Throughout Progression Into GVHD

NCT03188601

Conditions
Alpha 1-Antitrypsin, Bone Marrow Transplant Failure, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +13 more
Locations
  • Hadassah Jerusalem, Center, Israel
  • Tel Aviv Sourasky Medical Center - Ichilov Hospital Tel Aviv, Center, Israel
  • Rambam MC Haifa, North, Israel
  • Soroka Medical Center Beersheba, South, Israel
View Trial Details
Completed

Oxidoreductive Balance and Lysosomal Activity in Cancer Patients.

NCT03470857

Conditions
Antioxidants, Ceroid Lipofuscinosis, Neuronal, 10, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +15 more
Locations
  • The Chair of Medical Biology, Collegium Medicum of Nicolaus Copernicus University Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Poland
  • Department of Nuclear Medicine of Center Oncology in Bydgoszcz Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Poland
  • Department of Positron Emission Tomography and Molecular Diagnostics, Collegium Medicum of Nicolaus Copernicus University Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Poland
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Completed

Phase 1 Study to Assess the Safety, PK and PD of INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency

NCT03815396

Conditions
AATD, Alpha-1 Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +10 more
Locations
  • UC Davis School of Medicine Sacramento, California, United States
  • University of Florida College of Medicine Gainesville, Florida, United States
  • University of Miami Miami, Florida, United States
  • Indiana University Indianapolis, Indiana, United States
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