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Clinical trial condition

alpha 1-Antitrypsin Deficiency

Explore clinical trials studying alpha 1-Antitrypsin Deficiency. Study availability and eligibility vary by location and protocol.

100 public trials 19 recruiting studies
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alpha 1-Antitrypsin Deficiency trial results

Recruiting

A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver Problems

NCT06512454

Conditions
Alpha1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • University of Florida Gainesville, Florida, United States
  • University of South Carolina Charleston, South Carolina, United States
  • Vanderbilt University Medical Center Nashville, Tennessee, United States
  • Vienna General Hospital (AKH Wien) Vienna, Austria
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Recruiting

A Study of AIR-001 in Adults With Alpha-1 Antitrypsin Deficiency (AATD)

NCT07431112

Conditions
Alpha 1 Antitrypsin Deficiency, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +11 more
Locations
  • Clinical Study Center Melbourne, Australia
  • Clinical Study Center 1 Tbilisi, Georgia
  • Clinical Study Center 2 Tbilisi, Georgia
  • Clinical Study Center Cambridge, United Kingdom
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Recruiting

Development of a Prediction Score for the Occurrence of Death or Lung Transplantation in Patients With Emphysema Secondary to Alpha-1-anti-tripsin Deficiency

NCT07715617

Conditions
Alpha-1-antitrypsin Deficiency, Artificial Intelligence (AI), Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +13 more
Locations
  • Hospices Civils de Lyon Bron, France
  • CHU de Lille Lille, France
  • Hôpital BICHAT CLAUDE-BERNARD Paris, France
  • Bordeaux University Hospital Pessac, France
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Recruiting

A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

NCT07227207

Conditions
Alpha-1 Antitrypsin Deficiency (AATD), Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Clinical Study Center Boston, Massachusetts, United States
  • Clinical Study Center Charleston, South Carolina, United States
  • Clinical Study Center Seattle, Washington, United States
  • Clinical Study Center Fitzroy, Victoria, Australia
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Recruiting

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

NCT07555483

Conditions
Alpha 1 Antitrypsin Deficiency, Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +14 more
Locations
  • GC2501 Study Site 106 Birmingham, Alabama, United States
  • GC2501 Study Site 102 Phoenix, Arizona, United States
  • GC2501 Study Site 107 Scottsdale, Arizona, United States
  • GC2501 Study Site 100 Los Angelas, California, United States
View all 22 locations
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Recruiting

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

NCT05677971

Conditions
Alpha1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • University of Alabama at Birmingham Birmingham, Alabama, United States
  • St. Joseph's Hospital and Medical Center Phoenix, Arizona, United States
  • Mayo Clinic Phoenix, Arizona, United States
  • University of Arizona Thomas D. Boyer Liver Institute Tucson, Arizona, United States
View all 89 locations
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Recruiting

A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)

NCT06389877

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Clinical Study Center Birmingham, Alabama, United States
  • Clinical Study Center Boston, Massachusetts, United States
  • Clinical Study Center Charleston, South Carolina, United States
  • Clinical Study Center Adelaide, Australia
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Recruiting

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

NCT06165341

Conditions
Alpha1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • St Joseph's Hospital and Medical Center Phoenix, Arizona, United States
  • Mayo Clinic - PPDS Phoenix, Arizona, United States
  • University of Arizona Thomas D. Boyer Liver Institute Tucson, Arizona, United States
  • University of California San Diego La Jolla, California, United States
View all 41 locations
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