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Enrolling by Invitation

NCT Number: NCT06868784

Investigation of the Relationship Between Executive Functions and Occupational Performance of Children With Duchenne Muscular Dystrophy

The effects of Duchenne muscular dystrophy and its treatments on executive functions and occupational performance are under-mentioned in the literature. The researches believe that developmental and cognitive research is needed to identify interventions for children with DMD to identify and adapt to both individual and social environments, including self-care, productivity and leisure activities. Therefore, the aim of this study was to examine executive functions and occupational performance in children with DMD and compare them with healthy controls.

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Key information

Conditions

Executive Dysfunction Congenital, Hereditary, and Neonatal Diseases and Abnormalities Duchenne Muscular Dystrophy Genetic Diseases, Inborn Genetic Diseases, X-Linked Muscular Diseases Muscular Disorders, Atrophic Muscular Dystrophies Muscular Dystrophy, Duchenne Musculoskeletal Diseases Nervous System Diseases Neuromuscular Diseases Occupational Problems

Age range

6 year–12 year

Sex eligibility

Male

Study type

Observational

Primary location

Lokman Hekim University

Ankara, Çankaya, 06510, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Being diagnosed with DMD
  • Volunteering to participate in the study by their parents and reading and signing the informed consent form

Exclusion criteria

  • Having a neuromuscular disease other than DMD and/or another diagnosed neuromuscular disease accompanying DMD
  • The family and/or the child has problems with cooperation in completing the assessments for any reason
  • Difficulty understanding and speaking the Turkish language

Treatment and study plan

Evaluations

Other

Evaluations of executive functions and occupational performance

Primary outcomes

  1. Demographic information form

    Time frame: one-time evaluation

  2. Brooke upper extremity functional scale

    Time frame: one-time evaluation

    It will be used to assess the functional level of the upper limbs of children with DMD. The classification consists of six stages and progression from the first to the sixth stage indicates a decrease in the functionality of the upper limb.

  3. Vignos lower extremity functional scale

    Time frame: one-time evaluation

    It will be used to assess the functional level of the lower limbs of children with DMD. The classification consists of ten stages and progression from the first to the tenth stage indicates a decrease in the functionality of the upper limb.

  4. The Childhood Executive Functioning Inventory

    Time frame: one-time evaluation

    This 26-item scale consists of 4 subscales: working memory (9 items), planning (6 items), inhibition (6 items) and regulation (5 items). Working memory and planning sub-dimensions constitute the total score of "working memory" and inhibition and regulation sub-dimensions constitute the total score of "inhibition". As the score obtained from the scale increases, the child's executive functions weaken.

  5. Canadian Occupational Performance Measure

    Time frame: one-time evaluation

    It will be used to assess children's occupational performance.

Sponsors and collaborators

Lead sponsor

Lokman Hekim University

Other Gov

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Mar 11, 2025
Registry last updated
Feb 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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