Skip to main content
OpenTrials
Recruiting

NCT Number: NCT03139786

Follow-up of a Cohort of Patients With Aortic Valve Bicuspidia

The aortic valve bicuspidia (BVA) is a congenital condition corresponding to the presence of 2 sigmoids instead of 3. This is the most common cardiac congenital anomaly affecting 0.5 to 2% of the population The general rule. BVA may be associated with structural damage to the ascending aorta, which exposes BVA patients to a risk of developing ascending aortic aneurysm and acute aortic accidents. Recent data from the literature have revealed that the natural history of BVA is marked by a possible development towards significant valvulopathy and / or an ascending aortic aneurysm often requiring surgical treatment. However, the natural history of bicuspid disease remains poorly understood and the prognostic factors for progression to severe valvulopathy and / or aneurysmal dilatation of the ascending aorta remain to be determined.

Recruiting

Interested in participating?

Request Info

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Amiens Picardie

Amiens, Picardie, 80054, France

Location status: Recruiting

Location contact

Christophe TRIBOUILLOY, PhD

CONTACT

[email protected]

+33322455885

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients examined in the echocardiography laboratory whose objective examination was a bicuspid valve of the aortic valve
  • Bicuspidia may be formerly known

Exclusion criteria

  • Refusal to participate
  • Patients who had already undergone bicuspid surgery or ascending aorta before being examined at the echocardiography laboratory

Treatment and study plan

Study the natural history of bicuspid

Other

Study the natural history of bicuspid

Primary outcomes

  1. Analysis of 10 year mortality in cardiac surgery in a patient with bicuspid

    Time frame: 10 years

    Analyzing the natural history of Bicuspidia

Study contacts

Contact information is provided by the study sponsor or research team.

Christophe TRIBOUILLOY, PhD

CONTACT

[email protected]

+33322455885

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Registry information

Official study title

Prospective Follow-up of a Cohort of Patients With Aortic Valve Bicuspidia: Multicentre Study

Important dates

Study start
2010
Primary completion
2035
Study completion
2035
First posted
May 4, 2017
Registry last updated
Jun 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.