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Recruiting

NCT Number: NCT02306200

Cardiovascular Health Improvement Project

The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.

Recruiting

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Key information

Conditions

Aortic Aneurysm Acute Aortic Syndrome Aneurysm Aortic Aneurysm, Abdominal Aortic Aneurysm, Thoracic Aortic Diseases Aortic Dissection Aortic Valve Disease Bicuspid Aortic Valve (BAV) Bicuspid Aortic Valve Disease Cardiovascular Abnormalities Cardiovascular Diseases Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Dissection, Blood Vessel Heart Defects, Congenital Heart Diseases Heart Failure Heart Valve Diseases Vascular Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls. The aims of the study are to collect biological specimens (blood, plasma, serum, aortic tissue) and family history; establish a biobank, establish a comprehensive database with information from consented patients, and provide researchers with high quality well annotated DNA samples with demographic and clinical information.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Any patient over the age of 18 who is able/willing to give informed consent
  • Patients <18 years of age with parental consent and assent (if assent is applicable for their age)
  • Diagnosis of:
  • aortic pathology potentially due to a known or suspected inherited condition
  • Idiopathic aortic aneurysm
  • Interesting of novel vascular pathology in the aorta or main branches
  • Family history of aortic or vascular disease
  • Other cardiovascular disease
  • Healthy controls with no apparent cardiovascular disease

Exclusion criteria

  • Not willing or able to sign the consent

Treatment and study plan

Primary outcomes

  1. Establishing a biobank of patients with Aortic Disease

    Time frame: 40 years

    Establish a biobank of blood, serum, plasma, tissue, and clinical data of patients with any form of aortic disease

Study contacts

Contact information is provided by the study sponsor or research team.

Jen McNamara, MS

CONTACT

[email protected]

734-232-6180

Lauren Humphrey-Stark, BS

CONTACT

[email protected]

7342324779

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Registry information

Acronym: CHIP

Important dates

Study start
2013
Primary completion
2053
Study completion
2053
First posted
Dec 3, 2014
Registry last updated
Apr 29, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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