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Clinical trial condition

Spinal Muscular Atrophy

Explore clinical trials studying Spinal Muscular Atrophy. Study availability and eligibility vary by location and protocol.

111 public trials 17 recruiting studies
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Spinal Muscular Atrophy trial results

Completed

European Registry of Patients With Infantile-onset Spinal Muscular Atrophy

NCT03339830

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Hopital Morvan - CHU de Brest Brest, France
  • Service de Rééducation Pédiatrique Infantile " L'Escale " - Hôpital Femme Mère Enfant Bron, France
  • Hôpital le Bocage - CHU Dijon Dijon, France
  • Maladie Neuromusculaire de l'enfant - Service Maladies infectieuses et neurologie infantile - Hôpital Roger Salengro Lille, France
View Trial Details
Completed

Characterization of the Clinical-epidemiological Profile of Patients With SMA5q Types II and III: Observational Study

NCT04404764

Conditions
Central Nervous System Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +9 more
Locations
  • Universidade Federal de Minas Gerais - Hospital das Clínicas Belo Horizonte, Brazil
  • Hospital de Clínicas da Universidade Estadual de Campinas - Unicamp Campinas, Brazil
  • Associação Hospitalar de Prot Infancia Dr Raul Carneiro - Hospital Infantil Pequeno Príncipe Curitiba, Brazil
  • Hospital Infantil Dr. Albert Sabin Fortaleza, Brazil
View Trial Details
Completed

An Open-label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy

NCT01703988

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Boston Children's Hospital Boston, Massachusetts, United States
  • Columbia University Medical Center New York, United States
  • UT Southwestern Medical Center - Children's Medical Center Dallas Dallas, Texas, United States
  • University of Utah School of Medicine Salt Lake City, Utah, United States
View Trial Details
Completed

An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA)

NCT01494701

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Children's Hospital Boston Boston, Massachusetts, United States
  • Columbia University Medical Center New York, United States
  • UT Southwestern Medical Center - Children's Medical Center Dallas Dallas, Texas, United States
  • University of Utah School of Medicine Salt Lake City, Utah, United States
View Trial Details
Completed

A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (SMA)

NCT01839656

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Stanford University Medical Center Stanford, California, United States
  • Nemours Children's Hospital Orlando, Florida, United States
  • Columbia University Medical Center New York, United States
  • The Hospital for Sick Children (SickKids) Toronto, Ontario, Canada
View Trial Details
Completed

A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants With Later-onset Spinal Muscular Atrophy (SMA)

NCT02292537

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • UCLA Clinical and Translational Research Center Los Angeles, California, United States
  • Lucile Packard Children's Hospital at Stanford Palo Alto, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Nemours Children's Hospital Orlando, Florida, United States
View all 24 locations
View Trial Details
Completed

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246)

NCT02052791

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Boston Children's Hospital Boston, Massachusetts, United States
  • Columbia University Medical Center New York, United States
  • UT Southwestern Medical Center - Children's Medical Center Dallas Dallas, Texas, United States
  • University of Utah School of Medicine Salt Lake City, Utah, United States
View Trial Details

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