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Paroxysmal Nocturnal Hemoglobinuria

Clinical trial condition

Paroxysmal Nocturnal Hemoglobinuria

Explore clinical trials studying Paroxysmal Nocturnal Hemoglobinuria. Study availability and eligibility vary by location and protocol.

91 public trials 12 recruiting studies

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Paroxysmal Nocturnal Hemoglobinuria trial results

Recruiting

A Study to Evaluate How Pozelimab + Cemdisiran Combination Therapy Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Whose Current Treatment is Not Working Efficiently

NCT07154745

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Hospital das Clinicas da FMRP USP Ribeirão Preto, São Paulo, Brazil

Faculdade de Medicina do ABC Santo André, São Paulo, Brazil

CISSS-CA Lévis, Quebec, Canada

Universita Cattolica del Sacro Cuore - Policlinico Universitario A. Gemelli Rome, Lazio, Italy

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Recruiting

A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works

NCT05744921

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Toronto General Hospital Toronto, Ontario, Canada

Hospital Pablo Tobon Uribe Medellín, Antioquia, Colombia

Semmelweis University/Semmelweis Egyetem Budapest, Hungary

Amrita Institute of Medical Sciences (AIMS) and Research Centre Aims Kochi, Kerala, India

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Recruiting

A Study of Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 Glomerulopathy

NCT07416162

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +23 more
Locations: Novartis Investigative Site Jeollanam, South Korea

Novartis Investigative Site Seoul, South Korea

Novartis Investigative Site Seoul, South Korea

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Recruiting

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

NCT06412497

Conditions: Acquired Amegakaryocytic Thrombocytopenia, Acquired Pure Red Cell Aplasia, Acquired amegakaryocytic thrombocytopenia, +11 more
Locations: University of Minnesota Masonic Cancer Center Minneapolis, Minnesota, United States

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Recruiting

A Multi-center, Ambispective Cohort Study to Evaluate the Impact of Iptacopan for Adult Patients With PNH in China

NCT06931691

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Novartis Investigative Site Hefei, Anhui, China

Novartis Investigative Site Guangzhou, Guangdong, China

Novartis Investigative Site Guangzhou, Guangdong, China

Novartis Investigative Site Shijiazhuang, Hebei, China

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Recruiting

Study of Safety and Efficacy of HS-10542 in Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT07470762

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: The First Affiliated Hospital，Zhejiang University School of Medicine Hangzhou, Zhejiang, China

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Recruiting

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

NCT06449001

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +10 more
Locations: Research Site Saskatoon, Saskatchewan, Canada

Research Site Paris, France

Research Site Leeds, United Kingdom

Research Site London, United Kingdom

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Recruiting

Home Reported Outcomes in PNH

NCT06411626

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Novartis Investigative Site East Hanover, New Jersey, United States

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Recruiting

Study of Safety and Efficacy of MY008211A in Patients With Residual Anemia Despite Anti-C5 Antibody Treatment

NCT06932471

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Peking Union Medical College Hospital (PUMCH). Beijing, Beijing Municipality, China

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Recruiting

Global PNH Patient Registry

NCT05755867

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Aplastic Anemia and MDS International Foundation Bethesda, Maryland, United States

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Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria trial results

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