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Paroxysmal Nocturnal Hemoglobinuria

Clinical trial condition

Paroxysmal Nocturnal Hemoglobinuria

Explore clinical trials studying Paroxysmal Nocturnal Hemoglobinuria. Study availability and eligibility vary by location and protocol.

89 public trials 13 recruiting studies

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Paroxysmal Nocturnal Hemoglobinuria trial results

Completed

A Study of Ravulizumab (ALXN1210) in Children and Adolescents With Paroxysmal Nocturnal Hemoglobinuria

NCT03406507

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Clinical Trial Site Atlanta, Georgia, United States

Clinical Trial Site Milwaukee, Wisconsin, United States

Clinical Trial Site Paris, France

Clinical Trial Site Utrecht, Netherlands

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Completed

A Long-Term Treatment Study of ACH-0144471 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

NCT03181633

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +16 more
Locations: Clinical Trial Site Avellino, Italy

Clinical Trial Site Naples, Italy

Clinical Trial Site Auckland, New Zealand

Clinical Trial Site Seoul, South Korea

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Completed

To Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Single and Multiple Doses of KP104

NCT05490017

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: CMAX Clinical Research Adelaide, Australia

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Completed

Open-label, Multiple Ascending Dose Study of Ravulizumab (ALXN1210) in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

NCT02605993

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +6 more
Locations: Clinical Trial Site Toronto, Ontario, Canada

Clinical Trial Site Lyon, Pierre-Bénite, France

Clinical Trial Site Lille, France

Clinical Trial Site Paris, France

View all 16 locations

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Completed

Unrelated Donor Stem Cell Transplantation

NCT01364363

Conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Anemia, +47 more
Locations: Scripps Green Hospital La Jolla, California, United States

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Completed

Nonmyeloablative Allogeneic Transplant

NCT01272817

Conditions: Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia, Adenocarcinoma, +91 more
Locations: Scripps Green Hospital La Jolla, California, United States

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Completed

A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With PNH

NCT04085601

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Julian Coronel Medical Center Cali, Colombia

Research Center of the Colombian Clinical Life Cancer Foundation Medellín, Colombia

Queen Mary Hospital Hong Kong

Princess Margaret Hospital Kwai Chung, Hong Kong

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Completed

The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT04079257

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +7 more
Locations: Radboudumc Nijmegen, Netherlands

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Completed

Study to Evaluate the Efficacy and Safety of APL-2 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

NCT03500549

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: University of Southern California Los Angeles, California, United States

Sarcoma Oncology Research Center Santa Monica, California, United States

Denver Health Denver, Colorado, United States

Georgetown University Hospital Washington D.C., District of Columbia, United States

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Completed

First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH

NCT04330534

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Study Site Vienna, Austria

Study Site Bloemfontein, South Africa

Study Site Pretoria, South Africa

Study Site London, United Kingdom

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