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Clinical trial condition

Hemoglobinuria, Paroxysmal

Explore clinical trials studying Hemoglobinuria, Paroxysmal. Study availability and eligibility vary by location and protocol.

164 public trials 28 recruiting studies
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Hemoglobinuria, Paroxysmal trial results

Recruiting

Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

NCT01174108

Conditions
Anemia, Anemia, Aplastic, Anemia, Hemolytic, +11 more
Locations
  • University of Maryland, Baltimore (UMB) Baltimore, Maryland, United States
  • National Institutes of Health Clinical Center Bethesda, Maryland, United States
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Recruiting

Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients

NCT06934967

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Cancer Institute of New Jersey New Brunswick, New Jersey, United States
  • St Jude Childrens Research Hospital Memphis, Tennessee, United States
  • Novartis Investigative Site Brasília, Federal District, Brazil
  • Novartis Investigative Site Natal, Rio Grande do Norte, Brazil
View all 15 locations
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Recruiting

A Study to Evaluate How Pozelimab + Cemdisiran Combination Therapy Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Whose Current Treatment is Not Working Efficiently

NCT07154745

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Hospital das Clinicas da FMRP USP Ribeirão Preto, São Paulo, Brazil
  • Faculdade de Medicina do ABC Santo André, São Paulo, Brazil
  • CISSS-CA Lévis, Quebec, Canada
  • Universita Cattolica del Sacro Cuore - Policlinico Universitario A. Gemelli Rome, Lazio, Italy
View all 20 locations
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Recruiting

A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works

NCT05744921

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Toronto General Hospital Toronto, Ontario, Canada
  • Hospital Pablo Tobon Uribe Medellín, Antioquia, Colombia
  • Semmelweis University/Semmelweis Egyetem Budapest, Hungary
  • Amrita Institute of Medical Sciences (AIMS) and Research Centre Aims Kochi, Kerala, India
View all 46 locations
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Recruiting

A First-in-Human Safety and Efficacy Study of ALN-CFB, a Small Interfering RNA (siRNA) Targeting Complement Factor B, in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria With Persistent Anemia on a C5 Inhibitor

NCT07187401

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +6 more
Locations
  • Toronto General Hospital Toronto, Ontario, Canada
  • St. Vincent Hospital - The Catholic University of Korea Suwon, Gyeonggi-do, South Korea
  • The Catholic University of Korea, Seoul St. Mary's Hospital Seoul, South Korea
  • Seoul National University Hospital Seoul, South Korea
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Recruiting

REAL-CARE: Real-world Effectiveness of Iptacopan in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT07229235

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Novartis Investigative Site Alessandria, AL, Italy
  • Novartis Investigative Site Avellino, AV, Italy
  • Novartis Investigative Site Brescia, BS, Italy
  • Novartis Investigative Site Florence, FI, Italy
View Trial Details

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