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Clinical trial condition

Hemoglobinuria, Paroxysmal

Explore clinical trials studying Hemoglobinuria, Paroxysmal. Study availability and eligibility vary by location and protocol.

166 public trials 28 recruiting studies
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Hemoglobinuria, Paroxysmal trial results

Active, not recruiting

Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT04747613

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • City Of Hope National Med Center Duarte, California, United States
  • City Of Hope Duarte, California, United States
  • USC Norris Cancer Center Los Angeles, California, United States
  • Univ Cali Irvine ALS Neuromuscular Orange, California, United States
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Active, not recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors

NCT04432584

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Carolinas Healthcare System Charlotte, North Carolina, United States
  • Nationwide Children's Hospital Columbus, Ohio, United States
  • Cliniques Universitaires Saint-Luc Brussels, Belgium
  • AZ Delta Campus Westlaan Roeselare, Belgium
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Active, not recruiting

A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH

NCT05389449

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +8 more
Locations
  • Research Site Los Angeles, California, United States
  • Research Site Chicago, Illinois, United States
  • Research Site Baltimore, Maryland, United States
  • Research Site Kansas City, Missouri, United States
View all 45 locations
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Active, not recruiting

A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment

NCT05133531

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • The Oncology Institute of Hope & Innovation Whittier, California, United States
  • Centro de Estudos e Pesquisas em Hematologia e Oncologia Santo André, São Paulo, Brazil
  • A Beneficencia Portuguesa de Sao Paulo, BP Mirante São Paulo, Brazil
  • Casa de Saude Santa Marcelina São Paulo, Brazil
View all 68 locations
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