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Clinical trial condition

Paroxysmal Nocturnal Hemoglobinuria

Explore clinical trials studying Paroxysmal Nocturnal Hemoglobinuria. Study availability and eligibility vary by location and protocol.

89 public trials 13 recruiting studies
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Paroxysmal Nocturnal Hemoglobinuria trial results

Active, Not Recruiting

Specified Drug-use Surveillance of Fabhalta Capsules

NCT06606314

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Novartis Investigative Site Handa, Aichi-ken, Japan
  • Novartis Investigative Site Nagoya, Aichi-ken, Japan
  • Novartis Investigative Site Nagoya, Aichi-ken, Japan
  • Novartis Investigative Site Okazaki, Aichi-ken, Japan
View all 91 locations
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Active, Not Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibition

NCT04654468

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • West China Hospital, Sichuan University Chengdu, China
  • Guangdong General Hospital Guangzhou, China
  • Institute of Hematology and Hospital of Blood Disease Tianjin, China
  • Tianjin Medical University General Hospital Tianjin, China
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Active, Not Recruiting

A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment

NCT05133531

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • The Oncology Institute of Hope & Innovation Whittier, California, United States
  • Centro de Estudos e Pesquisas em Hematologia e Oncologia Santo André, São Paulo, Brazil
  • A Beneficencia Portuguesa de Sao Paulo, BP Mirante São Paulo, Brazil
  • Casa de Saude Santa Marcelina São Paulo, Brazil
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Active, Not Recruiting

A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors

NCT04434092

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Organizacion Medica de Investigacion (OMI) Ciudad Autonoma Buenos Aires, Argentina
  • *X*CEPHO - Centro de Estudos e Pesquisas em Hematologia e Oncologia Santo André, São Paulo, Brazil
  • Beneficencia Portuguesa de Sao Paulo São Paulo, Brazil
  • Peking Union Medical College Hospital Beijing, China
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Active, Not Recruiting

To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of KP104

NCT05476887

Conditions
Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations
  • Peking Union Medical College Hospital Beijing, China
  • Jiangsu Province Hospital Nanjing, China
  • Chinese Academy of Medical Sciences Peking Union Medical College - Institute of Hematology Blood Diseases Hospital Tianjin, China
  • Henan Cancer Hospital Zhengzhou, China
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