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Clinical trial condition

Motor Neuron Disease

Explore clinical trials studying Motor Neuron Disease. Study availability and eligibility vary by location and protocol.

839 public trials 197 recruiting studies
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Motor Neuron Disease trial results

Active, Not Recruiting

A Study to Learn About the Effect of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Risdiplam (ASCEND)

NCT05067790

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Barrow Neurological Institute Phoenix, Arizona, United States
  • Stanford Neuroscience Health Center Palo Alto, California, United States
  • Rare Disease Research, LLC Atlanta, Georgia, United States
  • Boston Children's Hospital Boston, Massachusetts, United States
View all 22 locations
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Active, Not Recruiting

A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

NCT05633459

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Universitaire Ziekenhuizen Leuven (UZ Leuven) Leuven, Belgium
  • University of Calgary Calgary, Alberta, Canada
  • University of Alberta Edmonton, Alberta, Canada
  • Sunnybrook Health Science Centre Toronto, Ontario, Canada
View all 15 locations
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Active, Not Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers and Participants With ALS

NCT05279755

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Massachusetts General Hospital Boston, Massachusetts, United States
  • Worldwide Clinical Trials Early Phase Services San Antonio, Texas, United States
  • The Neuro - Montréal Neurological Institute-Hospital Montreal, Quebec, Canada
  • University Medical Center Utrecht Utrecht, Netherlands
View Trial Details
Active, Not Recruiting

A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)

NCT06441682

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • UZ Leuven Leuven, Belgium
  • Kaye Edmonton Clinic Edmonton, Canada
  • Montreal Neurological Institute and Hospital Montreal, Canada
  • Aarhus Universitets Hospital Aarhus, Denmark
View Trial Details
Active, Not Recruiting

ALS Diagnosis From a Saliva Sample: a Non-coding RNA Analysis Approach

NCT05928416

Conditions
Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis, Sporadic, Amyotrophic lateral sclerosis 1, +10 more
Locations
  • CHU Strasbourg Strasbourg, Alsace, France
  • CHU Nantes Saint-Herblain, Loire-Atlantique, France
  • C.H.U. de Saint-Étienne Saint-Étienne-de-Montluc, Pays de la Loire Region, France
  • Hospices Civils de Lyon Bron, Rhône, France
View all 19 locations
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Active, Not Recruiting

HABIT-ILE + FST in Children With SMA

NCT07223320

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Center for Cerebral Palsy Research, Teachers College, Columbia University New York, United States
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Active, Not Recruiting

Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS

NCT04057898

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • University of California Orange, California, United States
  • Mayo Clinic Jacksonville, Florida, United States
  • Augusta University Augusta, Georgia, United States
  • Indiana University IU Health Neuroscience Center Indianapolis, Indiana, United States
View all 16 locations
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