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Clinical trial condition

Motor Neuron Disease

Explore clinical trials studying Motor Neuron Disease. Study availability and eligibility vary by location and protocol.

839 public trials 197 recruiting studies
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Motor Neuron Disease trial results

Active, Not Recruiting

A Study to Learn About the Safety of BIIB115 Injections and How BIIB115 is Processed in the Bodies of Healthy Adult Male Volunteers and of Pediatric Participants With Spinal Muscular Atrophy Who Previously Took Onasemnogene Abeparvovec

NCT05575011

Conditions
Central Nervous System Diseases, Healthy Volunteer, Motor Neuron Disease, +5 more
Locations
  • Universitair Ziekenhuis Gent Ghent, Belgium
  • Children's Hospital of Eastern Ontario Ontario, Canada
  • Hôpital Armand Trousseau Paris, France
  • Universitatsklinikum Essen Essen, Germany
View all 17 locations
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Active, Not Recruiting

Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials

NCT05335876

Conditions
Atrophy, Bulbo-Spinal Atrophy, X-Linked, Central Nervous System Diseases, +19 more
Locations
  • Child Hosp Of The Kings Daughters Norfolk, Virginia, United States
  • Novartis Investigative Site Sydney, New South Wales, Australia
  • Novartis Investigative Site Leuven, Belgium
  • Novartis Investigative Site Curitiba, Paraná, Brazil
View all 32 locations
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Active, Not Recruiting

Early Check: Expanded Screening in Newborns

NCT03655223

Conditions
17 Alpha-Hydroxylase Deficiency, 3-Hydroxy-3-Methylglutaric Aciduria, 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, +456 more
Locations
  • RTI International Research Triangle Park, North Carolina, United States
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Active, Not Recruiting

A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy

NCT05115110

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Nemours Children's Hospital Orlando, Florida, United States
  • Boston Childrens Hospital Boston, Massachusetts, United States
  • Columbia University Medical Center New York, United States
  • Neurology & Neuromuscular Care Center Flower Mound, Texas, United States
View all 35 locations
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Active, Not Recruiting

A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy

NCT05337553

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +6 more
Locations
  • Phoenix Children's Phoenix, Arizona, United States
  • UCSD & Rady Children's La Jolla, California, United States
  • Children's Hospital of Los Angeles Los Angeles, California, United States
  • UCSF Benioff Children's Hospital, Medical Center San Francisco, California, United States
View all 53 locations
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