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Clinical trial condition

Motor Neuron Disease

Explore clinical trials studying Motor Neuron Disease. Study availability and eligibility vary by location and protocol.

856 public trials 198 recruiting studies
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Motor Neuron Disease trial results

Recruiting

A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis.

NCT07369076

Conditions
Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +9 more
Locations
  • Concord Repatriation General Hospital Concord, New South Wales, Australia
  • Neuroscience Research Australia Randwick, New South Wales, Australia
  • Royal Brisbane and Women's Hospital Brisbane, Queensland, Australia
  • Flinders Medical Centre Bedford Park, South Australia, Australia
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Recruiting

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

NCT07002034

Conditions
Adjustment Disorder, Adjustment Disorders, Amyotrophic Lateral Sclerosis, +28 more
Locations
  • UAB, Psychiatry and Behavioral Neurology Birmingham, Alabama, United States
  • University of Arizona Tucson, Arizona, United States
  • Kadima Neuropsychiatry Institute San Diego, California, United States
  • Providence Medical Foundation Santa Rosa, California, United States
View all 32 locations
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Recruiting

A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

NCT07047144

Conditions
Anti-myostatin, Central Nervous System Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +17 more
Locations
  • Phoenix Children's Hospital Phoenix, Arizona, United States
  • Children's Hospital of Orange County (CHOC) Orange, California, United States
  • Stanford Neuroscience Health Center (SNHC) Palo Alto, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
View all 24 locations
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Recruiting

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

NCT07287982

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
  • Rady Childrens Hospital San Diego, California, United States
  • Stanford University Medical Center Stanford, California, United States
  • Connecticut Children's Medical Center Hartford, Connecticut, United States
View all 23 locations
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Recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

NCT06351592

Conditions
Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +10 more
Locations
  • Concord Repatriation General Hospital Concord, New South Wales, Australia
  • Macquarie University Sydney, New South Wales, Australia
  • Sunshine Coast University Hospital Birtinya, Queensland, Australia
  • KU Leuven Leuven, Vlaams-Brabant, Belgium
View all 22 locations
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Recruiting

Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS

NCT07287397

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • St Joseph's Hospital and medical Center - Barrow Neurological Institute Phoenix, Arizona, United States
  • University of California San Diego Medical Center San Diego, California, United States
  • Mayo Clinic in Florida Jacksonville, Florida, United States
  • University of Miami School of Science Miami, Florida, United States
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Recruiting

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

NCT05861999

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • University of Arkansas for Medical Sciences Little Rock, Arkansas, United States
  • Valley Children's Hospital Madera, California, United States
  • Stanford Univ Medical Center Palo Alto, California, United States
  • Children's Hospital of Colorado Aurora, Colorado, United States
View all 19 locations
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