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Clinical trial condition

Motor Neuron Disease

Explore clinical trials studying Motor Neuron Disease. Study availability and eligibility vary by location and protocol.

839 public trials 197 recruiting studies
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Motor Neuron Disease trial results

Recruiting

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

NCT06764485

Conditions
Bulbo-Spinal Atrophy, X-Linked, Central Nervous System Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +20 more
Locations
  • Central Alabama Research Birmingham, Alabama, United States
  • Banner MD Anderson Cancer Center Gilbert, Arizona, United States
  • Local Institution - 0370 Anaheim, California, United States
  • Moores Cancer Center La Jolla, California, United States
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Recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

NCT06351592

Conditions
Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +10 more
Locations
  • Concord Repatriation General Hospital Concord, New South Wales, Australia
  • Macquarie University Sydney, New South Wales, Australia
  • Sunshine Coast University Hospital Birtinya, Queensland, Australia
  • KU Leuven Leuven, Vlaams-Brabant, Belgium
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Recruiting

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

NCT07287982

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
  • Rady Childrens Hospital San Diego, California, United States
  • Stanford University Medical Center Stanford, California, United States
  • Connecticut Children's Medical Center Hartford, Connecticut, United States
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Recruiting

HD-tDCS in Amyotrophic Lateral Sclerosis: A Multicenter Randomized Controlled Trial

NCT06719947

Conditions
Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +9 more
Locations
  • Universidade de Brasília - Campus Ceilândia Brasília, Federal District, Brazil
  • PneumoCardioVascular Lab - HUOL/UFRN Natal, Rio Grande do Norte, Brazil
  • Universidad Autónoma de Chile Santiago, Santiago Metropolitan, Chile
  • Universidad do Chile Santiago, Santiago Metropolitan, Chile
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Recruiting

A Substudy of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis

NCT07571174

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • UZ Leuven Leuven, Belgium
  • University Hospital - London Health Sciences Centre London, Canada
  • McGill University Health Centre Montreal, Canada
  • Sunnybrook Research Institute Toronto, Canada
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Recruiting

A Master Protocol (OLMP): A Study of LY4256984 in Participants With Amyotrophic Lateral Sclerosis (ALS)

NCT07571200

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • UZ Leuven Leuven, Belgium
  • University Hospital - London Health Sciences Centre London, Canada
  • McGill University Health Centre Montreal, Canada
  • Sunnybrook Research Institute Toronto, Canada
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Recruiting

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

NCT05861999

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • University of Arkansas for Medical Sciences Little Rock, Arkansas, United States
  • Valley Children's Hospital Madera, California, United States
  • Stanford Univ Medical Center Palo Alto, California, United States
  • Children's Hospital of Colorado Aurora, Colorado, United States
View all 19 locations
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