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Clinical trial condition

Motor Neuron Disease

Explore clinical trials studying Motor Neuron Disease. Study availability and eligibility vary by location and protocol.

839 public trials 197 recruiting studies
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Motor Neuron Disease trial results

Active, Not Recruiting

International SBMA Project (KDA)

NCT07443449

Conditions
Bulbo-Spinal Atrophy, X-Linked, Central Nervous System Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +11 more
Locations
  • Fondazione IRCCS Istituto Neurologico Carlo Besta Milan, Italy
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Active, Not Recruiting

A Study to Learn About the Long-Term Safety of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Took Part in an Earlier Nusinersen Trial (ONWARD)

NCT04729907

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Stanford University Medical Center Sacramento, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
  • The Johns Hopkins Hospital Baltimore, Maryland, United States
View all 37 locations
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Active, Not Recruiting

ALS Phase II Study of NX210c

NCT06365216

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Centre Hospitalier Regional Et Universitaire De Brest Brest, France
  • Centre Hospitalier Universitaire De Caen Normandie Caen, France
  • Hôpital La Timone - APHM Marseille, France
  • CHRU De Nancy Nancy, France
View all 16 locations
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Active, Not Recruiting

An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS

NCT05299658

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Concord Hospital Concord, New South Wales, Australia
  • Neuroscience Research Australia Randwick, New South Wales, Australia
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Active, Not Recruiting

Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA®

NCT04159987

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • CHU de Lyon Lyon, Auvergne-Rhône-Alpes, France
  • CHRU de Lille Lille, Hauts-de-France, France
  • CHU de Montpellier Montpellier, Occitanie, France
  • CHU de Toulouse Toulouse, Occitanie, France
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Active, Not Recruiting

A Clinical Study Evaluating the Safety and Efficacy of SKG0201 Injection in Patients With Spinal Muscular Atrophy Type 1

NCT06191354

Conditions
Central Nervous System Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +9 more
Locations
  • West China Sencond Hospital, Sichuan University / West China women's and children's Hospital Chengdu, Sichuan, China
  • Xinhua Hospital Affiliated To Shanghai Jiao Tong University School Of Medicine Shanghai, China
  • National Children's Medical Center, Children's Hospital of Fudan University Shanghai, China
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Active, Not Recruiting

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

NCT06100276

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Barrow Neurological Institute Phoenix, Arizona, United States
  • University of California Irvine Irvine, California, United States
  • California Pacific Medical Center San Francisco, California, United States
  • Mayo Clinic Florida Jacksonville, Florida, United States
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