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Clinical trial condition

Hypophosphatasia

Explore clinical trials studying Hypophosphatasia. Study availability and eligibility vary by location and protocol.

35 public trials 6 recruiting studies
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Hypophosphatasia trial results

Recruiting

Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)

NCT05596539

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Enthesopathy, Genetic Diseases, Inborn, +10 more
Locations
  • CHU de Bordeaux- Hôpital Pellegrin Place Amélia Raba Léon - 12è étage - Rhumatologie - Bordeaux, France
  • CHU Lille Lille, France
  • Hospices Civils de Lyon Lyon, France
  • CHU Nice Nice, France
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Recruiting

A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALE1 in Healthy Adults and Adults With Hypophosphatasia in Order to Identify Suitable Doses of ALE1

NCT07179640

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hypophosphatasia, +5 more
Locations
  • New Zealand Clinical Research Grafton, Auckland, New Zealand
  • Fortrea Clinical Research Unit Leeds, United Kingdom
  • Universitätsklinikum Würzburg Würzburg, Germany
View Trial Details
Recruiting

A Prospective Sub-Study of the Global Hypophosphatasia Registry

NCT05234567

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hypophosphatasia, +4 more
Locations
  • Clinical Trial Site Hartford, Connecticut, United States
  • Clinical Trial Site Chicago, Illinois, United States
  • Clinical Trial Site Boston, Massachusetts, United States
  • Clinical Trial Site Kansas City, Missouri, United States
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Recruiting

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center Study

NCT06574282

Conditions
Bone Diseases, Bone Diseases, Metabolic, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +11 more
Locations
  • Clinic of Internal Medicine III, Department of Oncology, Haematology, Rheumatology and Clinical Immunology, University Hospital Bonn Bonn, North Rhine-Westphali, Germany
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Enrolling by invitation

Registry of Patients With Hypophosphatasia

NCT02306720

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hypophosphatasia, +5 more
Locations
  • Research Site Centennial, Colorado, United States
  • Research Site Hartford, Connecticut, United States
  • Research Site Tampa, Florida, United States
  • Research Site Decatur, Georgia, United States
View all 64 locations
View Trial Details
Active, not recruiting

Early Check: Expanded Screening in Newborns

NCT03655223

Conditions
17 Alpha-Hydroxylase Deficiency, 3-Hydroxy-3-Methylglutaric Aciduria, 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, +456 more
Locations
  • RTI International Research Triangle Park, North Carolina, United States
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Active, not recruiting

Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa

NCT06079281

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hypophosphatasia, +4 more
Locations
  • Research Site Indianapolis, Indiana, United States
  • Research Site Garden City, New York, United States
  • Research Site Durham, North Carolina, United States
  • Research Site Columbus, Ohio, United States
View all 65 locations
View Trial Details

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