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Clinical trial condition

Hypophosphatasia

Explore clinical trials studying Hypophosphatasia. Study availability and eligibility vary by location and protocol.

25 public trials 5 recruiting studies
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Hypophosphatasia trial results

Recruiting

Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)

NCT05596539

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Enthesopathy, Genetic Diseases, Inborn, +10 more
Locations
  • CHU de Bordeaux- Hôpital Pellegrin Place Amélia Raba Léon - 12è étage - Rhumatologie - Bordeaux, France
  • CHU Lille Lille, France
  • Hospices Civils de Lyon Lyon, France
  • CHU Nice Nice, France
View Trial Details
Recruiting

A Prospective Sub-Study of the Global Hypophosphatasia Registry

NCT05234567

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hypophosphatasia, +4 more
Locations
  • Clinical Trial Site Hartford, Connecticut, United States
  • Clinical Trial Site Chicago, Illinois, United States
  • Clinical Trial Site Boston, Massachusetts, United States
  • Clinical Trial Site Kansas City, Missouri, United States
View Trial Details
Recruiting

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center Study

NCT06574282

Conditions
Bone Diseases, Bone Diseases, Metabolic, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +11 more
Locations
  • Clinic of Internal Medicine III, Department of Oncology, Haematology, Rheumatology and Clinical Immunology, University Hospital Bonn Bonn, North Rhine-Westphali, Germany
View Trial Details
Active, not recruiting

Early Check: Expanded Screening in Newborns

NCT03655223

Conditions
17 Alpha-Hydroxylase Deficiency, 3-Hydroxy-3-Methylglutaric Aciduria, 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, +456 more
Locations
  • RTI International Research Triangle Park, North Carolina, United States
View Trial Details
Active, not recruiting

Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa

NCT06079281

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hypophosphatasia, +4 more
Locations
  • Research Site Indianapolis, Indiana, United States
  • Research Site Garden City, New York, United States
  • Research Site Durham, North Carolina, United States
  • Research Site Columbus, Ohio, United States
View all 65 locations
View Trial Details
Active, not recruiting

Phase 3 Study of ALXN1850 in Treatment-Naïve Pediatric Participants With HPP

NCT06079359

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hypophosphatasia, +4 more
Locations
  • Research Site Baltimore, Maryland, United States
  • Research Site Kansas City, Missouri, United States
  • Research Site Durham, North Carolina, United States
  • Research Site Nedlands, Australia
View all 32 locations
View Trial Details
Active, not recruiting

Phase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa

NCT06079372

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hypophosphatasia, +4 more
Locations
  • Research Site Hartford, Connecticut, United States
  • Research Site Baltimore, Maryland, United States
  • Research Site Minneapolis, Minnesota, United States
  • Research Site Kansas City, Missouri, United States
View all 21 locations
View Trial Details

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