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Clinical trial condition

Hypophosphatasia

Explore clinical trials studying Hypophosphatasia. Study availability and eligibility vary by location and protocol.

35 public trials 6 recruiting studies
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Hypophosphatasia trial results

Completed

Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP)

NCT02797821

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Hypophosphatasia, +4 more
Locations
  • Shriners Hospitals for Children St Louis, Missouri, United States
  • Duke University Medical Center Durham, North Carolina, United States
  • Vanderbilt Medical Center Endocrinology Nashville, Tennessee, United States
  • University of Würzburg Würzburg, Germany
View Trial Details
Completed

A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)

NCT01419028

Conditions
Avitaminosis, Bone Diseases, Bone Diseases, Metabolic, +16 more
Locations
  • Cedars-Sinai Medical Center Los Angeles, California, United States
  • Indiana University school of medicine Indianapolis, Indiana, United States
  • Shriners Hospital for Children St Louis, Missouri, United States
  • Oregon Health & Science University Portland, Oregon, United States
View Trial Details
Completed

Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)

NCT00744042

Conditions
Avitaminosis, Bone Diseases, Bone Diseases, Metabolic, +16 more
Locations
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
  • Alfred I. duPont Hospital for Children Wilmington, Delaware, United States
  • St. John's Hospital Springfield, Missouri, United States
  • University of Nebraska Medical Center, Munroe-Meyer Institute Omaha, Nebraska, United States
View Trial Details
Completed

Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)

NCT00739505

Conditions
Avitaminosis, Bone Diseases, Bone Diseases, Metabolic, +16 more
Locations
  • Barnes Jewish Hospital- Washington University School of Medicine St Louis, Missouri, United States
  • Duke University Medical Center Durham, North Carolina, United States
  • Department of Pediatrics & Child Health, Health Sciences Centre Winnipeg, University of Manitoba Winnipeg, Manitoba, Canada
View Trial Details
Completed

Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)

NCT01205152

Conditions
Avitaminosis, Bone Diseases, Bone Diseases, Metabolic, +15 more
Locations
  • Alfred I. DuPont Hospital for Children Wilmington, Delaware, United States
  • St. John's Medical Research Institute Springfield, Missouri, United States
  • University of Nebraska Medical Center Omaha, Nebraska, United States
  • Vanderbilt University Medical Center Nashville, Tennessee, United States
View Trial Details

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