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Clinical trial condition

Homozygous Familial Hypercholesterolemia

Explore clinical trials studying Homozygous Familial Hypercholesterolemia. Study availability and eligibility vary by location and protocol.

57 public trials 10 recruiting studies
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Homozygous Familial Hypercholesterolemia trial results

Completed

Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

NCT04681170

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Genetic Diseases, Inborn, +10 more
Locations
  • Universtiats-Kinderlinik Heidelberg Heidelberg, Baden-Wurttemberg, Germany
  • University Hospital of Cologne Cologne, Germany
  • University Medical Center Hamburg-Eppendorf Hamburg, Germany
  • Chaim Sheba Medical Center Ramat Gan, Israel
View Trial Details
Completed

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry

NCT03110432

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Dyslipoproteinemias, +14 more
Locations
  • Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany
  • Innere Medizin IV - Diabetologie, Endokrinologie und Nephrologie am Universitaetsklinikum Tübingen, Germany
  • Nephrologisches Zentrum Villingen-Schwenningen, Germany
View Trial Details
Completed

Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia

NCT03409744

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Genetic Diseases, Inborn, +9 more
Locations
  • Clinical Trial Site Los Angeles, California, United States
  • Clinical Trial Site Boca Raton, Florida, United States
  • Clinical Trial Site Boston, Massachusetts, United States
  • Clinical Trial Site New York, United States
View all 38 locations
View Trial Details
Completed

Evaluate the Efficacy and Safety of Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia

NCT04233918

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Genetic Diseases, Inborn, +9 more
Locations
  • Regeneron Research Site Wilmington, Delaware, United States
  • Regeneron Research Site Boca Raton, Florida, United States
  • Regeneron Research Site Kansas City, Kansas, United States
  • Regeneron Research Center Boston, Massachusetts, United States
View Trial Details
Completed

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

NCT02624869

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Familial Hypercholesterolemia, +11 more
Locations
  • Research Site The Bronx, New York, United States
  • Research Site Cincinnati, Ohio, United States
  • Research Site Nashville, Tennessee, United States
  • Research Site Camperdown, New South Wales, Australia
View all 46 locations
View Trial Details
Completed

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

NCT01624142

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Genetic Diseases, Inborn, +11 more
Locations
  • Research Site Los Angeles, California, United States
  • Research Site New York, United States
  • Research Site New York, United States
  • Research Site New York, United States
View all 44 locations
View Trial Details
Completed

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

NCT03814187

Conditions
ASCVD, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, +13 more
Locations
  • Research Site 10001-015 Birmingham, Alabama, United States
  • Research Site 10001-138 Foley, Alabama, United States
  • Research Site 10001-113 Huntsville, Alabama, United States
  • Research Site 10001-058 Mobile, Alabama, United States
View all 238 locations
View Trial Details
Completed

Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in HoFH

NCT04034485

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Genetic Diseases, Inborn, +9 more
Locations
  • NorthShore University Health System Evanston, Illinois, United States
  • Metabolic & Atherosclerosis Research Center (MARC) Cincinnati, Ohio, United States
  • VMMC & Safdarjung Hospital Delhi, National Capital Territory of Delhi, India
  • CIMS Hospital Pvt. Ltd Ahmedabad, India
View Trial Details

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