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Clinical trial condition

Heredodegenerative Disorders, Nervous System

Explore clinical trials studying Heredodegenerative Disorders, Nervous System. Study availability and eligibility vary by location and protocol.

1,876 public trials 411 recruiting studies
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Heredodegenerative Disorders, Nervous System trial results

Active, Not Recruiting

GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease

NCT05686551

Conditions
Basal Ganglia Diseases, Brain Diseases, Central Nervous System Diseases, +13 more
Locations
  • Uab Medicine Birmingham, Alabama, United States
  • Barrow Neurological Institute Phoenix, Arizona, United States
  • University of California Davis Medical System Sacramento, California, United States
  • CenExel Rocky Mountain Clinical Research, LLC Englewood, Colorado, United States
View all 70 locations
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Active, Not Recruiting

Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas

NCT05101148

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Rochester, Minnesota, United States
  • Research Site Akron, Ohio, United States
  • Research Site Bydgoszcz, Poland
  • Research Site Gdansk, Poland
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Active, Not Recruiting

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

NCT01089101

Conditions
Astrocytoma, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +25 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • Lucile Packard Children's Hospital Stanford University Palo Alto, California, United States
  • UCSF Medical Center-Mount Zion San Francisco, California, United States
  • UCSF Medical Center-Parnassus San Francisco, California, United States
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Active, Not Recruiting

Prescreening Study to Identify Potential Wilson Disease Participants for Gene-Editing Clinical Trial

NCT07226622

Conditions
Basal Ganglia Diseases, Brain Diseases, Brain Diseases, Metabolic, +16 more
Locations
  • University of California Los Angeles Medical Center Los Angeles, California, United States
  • University of California Davis Health Sacramento, California, United States
  • Yale New Haven Hospital New Haven, Connecticut, United States
  • Northwestern University Chicago, Illinois, United States
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Active, Not Recruiting

Study of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's Disease

NCT06873334

Conditions
Basal Ganglia Diseases, Brain Diseases, Central Nervous System Diseases, +17 more
Locations
  • John Hunter Hospital New Lambton Heights, New South Wales, Australia
  • Westmead Hospital Westmead, New South Wales, Australia
  • The University of Queensland Herston, Queensland, Australia
  • Flinders Medical Centre Adelaide, South Australia, Australia
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