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Clinical trial condition

Heredodegenerative Disorders, Nervous System

Explore clinical trials studying Heredodegenerative Disorders, Nervous System. Study availability and eligibility vary by location and protocol.

1,879 public trials 409 recruiting studies
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Heredodegenerative Disorders, Nervous System trial results

Completed

Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment

NCT02055118

Conditions
Carbohydrate Metabolism, Inborn Errors, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Connective Tissue Diseases, +23 more
Locations
  • Children's Hospital and Research Center at Oakland Oakland, California, United States
  • Ann & Robert H Lurie Children's Hospital of Chicago Chicago, Illinois, United States
  • University of North Carolina Chapel Hill, North Carolina, United States
  • Women's and Children's Hospital, 72 King William Road North Adelaide, Australia
View Trial Details
Completed

Extension of Study TKT024 Evaluating Long-Term Safety and Clinical Outcomes in MPS II Patients Receiving Idursulfase

NCT00630747

Conditions
Carbohydrate Metabolism, Inborn Errors, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Connective Tissue Diseases, +24 more
Locations
  • St. Joseph's Hospital Phoenix, Arizona, United States
  • Pediatric Clinical Research Center, Children's Hospital Oakland Oakland, California, United States
  • The Children's Hospital Denver, Colorado, United States
  • Harbin Clinic Rome, Georgia, United States
View all 52 locations
View Trial Details
Completed

Iduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II)

NCT00069641

Conditions
Carbohydrate Metabolism, Inborn Errors, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Connective Tissue Diseases, +22 more
Locations
  • Children's Hospital Oakland Oakland, California, United States
  • St. Louis Children's Hospital, Washington University St Louis, Missouri, United States
  • University of North Carolina at Chapel Hill Chapel Hill, North Carolina, United States
  • Texas Children's Hospital, Baylor College of Medicine Houston, Texas, United States
View Trial Details
Completed

Collection and Study of Cerebrospinal Fluid in Patients With Hunter Syndrome

NCT01449240

Conditions
Carbohydrate Metabolism, Inborn Errors, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Connective Tissue Diseases, +17 more
Locations
  • Emory University Decatur, Georgia, United States
  • Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
  • Children's Hospitals and Clinics of Minnesota Minneapolis, Minnesota, United States
  • University of North Carolina, Division of Genetics and Metabolism Chapel Hill, North Carolina, United States
View Trial Details
Completed

Safety and Clinical Outcomes in Hunter Syndrome Patients 5 Years of Age and Younger Receiving Idursulfase Therapy

NCT00607386

Conditions
Carbohydrate Metabolism, Inborn Errors, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Connective Tissue Diseases, +24 more
Locations
  • Hospital de Clinicas de Porto Alegre, Servico de Genetica Medica Porto Alegre, Rio Grande do Sul, Brazil
  • Instytut Pomnik Centrum Zdrowia Dziecka, Klinika Chorob Metaboliczynch, Endokrynologii i Diabetologii Warsaw, Poland
  • National Taiwan University Hospital, Dept. of Pediatrics and Medical Genetics Taipei, Taiwan
View Trial Details
Completed

Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD in Pediatric Patients With Early Stage MPS IIIA Disease

NCT02060526

Conditions
Carbohydrate Metabolism, Inborn Errors, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Connective Tissue Diseases, +18 more
Locations
  • Los Angeles Biomedical Research Torrance, California, United States
  • University of Minnesota Department of Pediatrics Minneapolis, Minnesota, United States
  • University of North Carolina Chapel Hill, North Carolina, United States
  • Hospital Universitario Austral A Unidad de Investigacion Buenos Aires, Argentina
View Trial Details
Completed

An Observational Study Evaluating Anti-Idursulfase Serum Antibody Response in Hunter Syndrome Patients

NCT00882921

Conditions
Carbohydrate Metabolism, Inborn Errors, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Connective Tissue Diseases, +23 more
Locations
  • Children's Hospital & Research Center Oakland Oakland, California, United States
  • Children's Hospitals and Clinics of Minnesota, Division of Genetics Minneapolis, Minnesota, United States
  • Hospital de Clinicas de Porto Alegre, Servico de Genetica Medica Porto Alegre, Rio Grande do Sul, Brazil
  • Birmingham Children's Hospital Birmingham, United Kingdom
View Trial Details
Completed

Safety and Pharmacology Study of VP 20629 in Adults With Friedreich's Ataxia

NCT01898884

Conditions
Brain Diseases, Central Nervous System Diseases, Cerebellar Diseases, +12 more
Locations
  • UCLA Medical Center Los Angeles, California, United States
  • University of South Florida Tampa, Florida, United States
  • Emory University Atlanta, Georgia, United States
  • University of Iowa Children's Hospital Iowa City, Iowa, United States
View Trial Details

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