Ohio State University
Columbus, Ohio, 43210, United States
Location status: Recruiting
Location contact
Deborah Hooper
CONTACT
Oscar Duran-Garnica, DDS, MS
CONTACT
NCT Number: NCT06017193
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited. Subjects who are treatment planned for extraction of a hopeless tooth and socket augmentation with bone graft and are planned for a dental implant surgery. The socket will be evaluated before the extraction and multi-time points during healing until an implant is placed with various evaluation tools, including ultrasound.
Interested in participating?
Request Info18 year and older
All sexes
Observational
Columbus, Ohio, 43210, United States
Location status: Recruiting
Deborah Hooper
CONTACT
Oscar Duran-Garnica, DDS, MS
CONTACT
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited. Subjects who are treatment planned for extraction of a hopeless tooth and socket augmentation with bone graft and are planned for a dental implant surgery. Qualified subjects will be asked during their pre-assessment visit. Subjects will be scanned with ultrasound and LASCA among other assessments shown in the info-graph and schedule of events. At the day of tooth extraction and socket augmentation (graft placement), clinical exams/measurements are taken, along with other research activities described in the info-graph and schedule of events. Recovery (checkups) from surgery will be monitored at 2 weeks, 1 month and 2 months, and 3 months. The timepoints additional to normal clinical timepoints are needed to gather potentially diagnostic valuable information about graft maturation, which in the future may lead to an early graft failure decision or trigger other clinical steps such as infection management.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: approximately 6 months
To determine if bone graft maturation can be imaged by ultrasound. Bone healing by ultrasound will be given a scale and will be compared to the reference standard micro-computed tomography (micro-CT) of tissue core biopsy taken at implant surgery
Time frame: approximately 6 months
To determine if bone graft maturation can be imaged by ultrasound, by comparing to clinical healing appearances. A score will be given to ultrasound image and clinical outcome and the correlation will be evaluated.
Contact information is provided by the study sponsor or research team.
University of Michigan
Other
Ultrasonic Imaging of Bone Graft Healing in Extraction Sockets for Precise and Personalized Implant Therapy (HUM00226516)
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06191510
Alveolar Bone Loss, Bone Diseases
Ribeirão Preto, São Paulo, Brazil
View Trial DetailsNCT06276335
Biomarkers, Dental Implant
London, United Kingdom
View Trial DetailsNCT05591651
Behavior, Breast Feeding
Osijek, Croatia
View Trial DetailsNCT07023757
Healing Wound
Ann Arbor, Michigan, United States
View Trial Details