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NCT Number: NCT06595628

Modified Guarnieri-Desarda Technique Versus Lichtenstein Technique in Inguinal Hernia Repair

The aim of this study is to compare the surgical outcome of both Lichnichtien tension free mesh hernioplasty of inguinal hernia and the combined modified Guarnieri Desarda technique in terms of postoperative pain, post operative complications (seroma, hematoma, wound infection), chronic inguinodenia, early recurrence and assessment of testicular vascularity and size by application of a testicular duplex and ultrasound.

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Key information

Conditions

Inguinal Hernia Hernia Hernia, Abdominal Hernia, Inguinal Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult male patients aged 18 years or older.
  • Patients diagnosed with non-complicated inguinal hernia (both direct and indirect).
  • Patients able to provide written informed consent to participate in the study.

Exclusion criteria

  • Patients younger than 18 years old.
  • Patients with complicated hernias (e.g., inflamed, obstructed, or strangulated hernias).
  • Patients with a recurrent inguinal hernia.
  • Patients with weak or thin external oblique aponeurosis (intraoperative findings).
  • Patients with a history of prior surgery in the inguinal region.
  • Patients who refuse to participate in the study.

Treatment and study plan

Lichtenstein Mesh-Based Hernioplasty

Procedure

This is a tension-free hernioplasty procedure that uses a synthetic mesh to reinforce the inguinal canal floor. The mesh is fixed to the inguinal ligament and internal oblique aponeurosis, creating a barrier to prevent hernia recurrence. It is considered the gold standard for inguinal hernia repair and is widely used for its effectiveness in reducing recurrence rates and postoperative complications.

Combined Modified Guarnieri-Desarda Tissue-Based Hernioplasty

Procedure

This technique combines elements of the Guarnieri and Desarda tissue-based repairs. It does not involve the use of synthetic mesh, relying instead on the patient's own tissues to reinforce the inguinal canal. The Guarnieri technique reshapes the internal ring to improve the inguinal canal's shutter mechanism, while the Desarda technique reinforces the posterior wall using the external oblique aponeurosis. This approach aims to preserve natural anatomy and minimize complications associated with mesh use.

Primary outcomes

  1. Postoperative Pain Assessment

    Time frame: At 2 weeks, 1 month, 3 months, and 6 months post-surgery.

    Postoperative pain will be evaluated using the Mankoski Pain Scale (0-10). Pain scores will be recorded at different time intervals to assess immediate and long-term postoperative pain, with scores from 0 to 2 considered negligible, and scores from 3 to 10 considered significant.

Secondary outcomes

  1. Incidence of Postoperative Complications

    Time frame: At 2 weeks, 1 month, and 3 months post-surgery.

    The occurrence of postoperative complications such as seroma, hematoma, wound infection, and testicular complications (e.g., hydrocele, cord induration) will be recorded and analyzed for each group.

  2. Hernia Recurrence Rate

    Time frame: At 6 months and 1 year post-surgery.

    The rate of hernia recurrence will be assessed through clinical examination and imaging, comparing recurrence between the Lichtenstein mesh-based repair group and the modified Guarnieri-Desarda tissue-based repair group.

  3. Testicular Vascularity

    Time frame: At 3 months post-surgery.

    Testicular vascularity will be evaluated using testicular duplex and ultrasound, comparing any changes pre- and post-surgery between the two groups.

Study contacts

Contact information is provided by the study sponsor or research team.

Fadi F. Khalil, MSc

CONTACT

[email protected]

01285612963 ext. +2

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Comparative Study of Modified Guarnieri-Desarda Technique Versus Lichtenstein Technique in Inguinal Hernia Repair

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Sep 19, 2024
Registry last updated
Mar 14, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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