CHU Clermont-Ferrand
Clermont-Ferrand, 63000, France
NCT Number: NCT06232837
Endotracheal intubation is a frequent procedure in the operating room but optimal Macintosh blade size remains unknown to date.
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Notify Me18 year and older
All sexes
Observational
Clermont-Ferrand, 63000, France
Endotracheal intubation is an extremely frequent procedure in the operating room, in intensive care units and in emergency medicine (in- or out-of-hospital). Apart from special cases of foreseen difficult programmed intubation, direct laryngoscopy remains the most frequently used technique. It requires the use of a handle (short or long), which serves as a light source on which is adapted a Macintosh curved blade, metallic or plastic, single or multiple use. The choice of blade size is based on the experience of the physician. Most often, in adult settings, size 3 or 4 blades are used. The very spartan literature on the subject and the current recommendations do not provide any information on the choice of blade size. Our team (and others) recently concluded that intubation first attempt rates in intensive care units or emergency settings were improved when using shorter Macintosh blade size No3 vs 4 (Godet et al. Intensive Care Medicine 2022 and Landefeld et al. Critical Care Explorations 2023). We therefore wish to evaluate these practices in terms of success of the first laryngoscopy, Cormack-Lehane and POGO (percentage of glottic opening visualized) scores, the need to use an alternative technique or a second operator in operative rooms. The results will be analyzed with regard as a function and experience of the person performing the laryngoscopy, as well as the setting (urgent or scheduled). These data are usually collected during the performance of an endotracheal intubation in a nationwide fashion in French operative rooms.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients in operative room requiring direct laryngoscopy for endotracheal intubation
Time frame: At intubation
The proportion of patients with successful first-pass orotracheal intubation
Time frame: At intubation
Rate of severe hypoxemia defined by lowest oxygen saturation (SpO2) < 90 %
Time frame: At intubation
Rate of cardiovascular collapse, defined as systolic blood pressure less than 80 mmHg systolic blood pressure less than 50 mmHg recorded at least once
Time frame: At intubation
Rate of cardiac arrest related to intubation
Time frame: At intubation
Rate of death related to intubation
Time frame: At intubation
Rate of difficult intubation
Time frame: At intubation
Rate of severe ventricular or supraventricular arrhythmia requiring intervention
Time frame: At intubation
Rate of oesophageal intubation
Time frame: At intubation
Rate of agitation
Time frame: At intubation
Rate of pulmonary aspiration
Time frame: At intubation
Rate of dental injuries
Time frame: During laryngoscopy
Cormack-Lehane grade of glottic view
Time frame: During laryngoscopy
Percentage of Glottic Opening (POGO) grade of glottic view
Time frame: During intubation
Rate of operator-assessed difficulty of intubation
Time frame: During intubation
Rate of need for additional airway equipment (video laryngoscope, bougie, stylet, fibroscope, cricothyrotomy)
Time frame: During intubation
Rate of need for a second operator
University Hospital, Clermont-Ferrand
Other
Macintosh Blade Size During Laryngoscopy for Endotracheal Intubation in Operative Rooms. A Nationwide Prospective Observational Study.
Acronym: MacSize_OR
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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