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OpenTrials
Completed

NCT Number: NCT06349005

Laryngoscopy and Coronary Artery Bypass Graft Surgery

In this prospective, randomized, controlled trial, the purpose is to compare Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope in terms of hemodynamic response associated with intubation in adult patients undergoing Coronary Artery Bypass Surgery (CABG).

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Key information

Conditions

Videolaryngoscopy

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Konya City Hospital

Konya, Turkey (Türkiye)

About this study

During endotracheal intubation, laryngoscopy can significantly affect hemodynamic responses, including tachycardia and elevated blood pressure, which may be particularly detrimental to individuals with cardiovascular conditions. Various studies have explored the hemodynamic reactions associated with laryngeal stimulation through different intubation devices. Researchers hypothesize that endotracheal intubation using video laryngoscopy will elicit a reduced hemodynamic response compared to traditional (Macintosh) laryngoscopy. In this prospective and randomized clinical study, the purpose is to compare the Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope concerning haemodynamic response associated with intubation in adult patients undergoing Coronary Artery Bypass Surgery (CABG).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age range between 18 and 75 years.
  • Scheduled for elective coronary artery bypass surgery.
  • Classified under American Society of Anesthesiologists (ASA) physical status II-III.
  • Patients with no history of difficult intubation or associated risk factors.

Exclusion criteria

  • Emergency case
  • Predicted difficult airways
  • Body mass index > 35 kilograms per meter squared
  • Baseline hemodynamic instability

Treatment and study plan

Tracheal intubation using Storz VL

Other

Video-assisted intubation technique using Storz VL

Tracheal intubation using Macintosh laryngoscopy

Other

Traditional intubation technique using Macintosh laryngoscopy

Tracheal intubation using MacGrath VL

Other

Video-assisted intubation technique using MacGrath VL

Tracheal intubation using EzVision VL

Other

Video-assisted intubation technique using EzVision VL

Primary outcomes

  1. Hemodynamic response

    Time frame: Change from baseline Systolic or Diastolic or mean Blood Pressure at 10 minutes

    Change from baseline invasive blood pressure

  2. Hemodynamic response

    Time frame: Change from baseline heart rate at 10 minutes

    Change from baseline heart rate

Secondary outcomes

  1. Intubation time

    Time frame: 180 seconds

    The duration from when the laryngoscope passes through the teeth until it is withdrawn back to the teeth will be measured.

  2. Visualization of the glottis

    Time frame: 180 seconds

    According to Cormack Lehane classification four grades (1-4). The higher the grade, the higher the likelihood of difficult intubation.

Sponsors and collaborators

Lead sponsor

Konya Meram State Hospital

Other

Registry information

Official study title

Hemodynamic Response to Various Laryngoscopes During Tracheal Intubation in CABG Patients

Acronym: VL

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Apr 5, 2024
Registry last updated
May 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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