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Completed

NCT Number: NCT06972394

Videolaryngoscopy at Unanticipated Difficult Airway

Glottic visualization, intubation success, complications and accidental esophageal intubation rate of direct laryngoscopy (DL) and videolaryngoscopy (VL) were compared in patients with UDA.

Completed

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Key information

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Tokat Gaziosmanpasa University

Tokat Province, Center, 60100, Turkey (Türkiye)

About this study

Ethical approval for this study was obtained from the Clinical Research Ethics Committee of Tokat Gaziosmanpaşa University (25-MOBAEK-124). Data were collected by reviewing hospital automation systems, patient records, and difficult airway forms for patients who underwent elective surgery under general anesthesia and experienced unanticipated difficult airway (UDA) between January 2020 and March 2025. Patients with incomplete data, a prior history of difficult airway, or preoperative findings indicating a difficult airway were excluded from the study. Demographic variables-including age, gender, body mass index, comorbidities, and ASA scores-as well as airway examination findings such as Mallampati scores and Cormack-Lehane grades, were analyzed. Additionally, intubation methods, instruments used, and challenges encountered during airway management were evaluated. The effects of direct laryngoscopy (DL) and videolaryngoscopy (VL) on glottic visualization, intubation success, and complication rates were also compared.

In the relevant clinic, preoperative airway evaluation is performed by assessing the Mallampati classification, thyromental distance, sternomental distance, inter-incisor gap and angle, neck circumference, atlanto-occipital joint mobility, upper lip bite test, retrognathia, prominent upper incisors, high and narrow palate, macroglossia, hoarseness, dyspnea on exertion, and history of difficult airway. In patients without any predictors of difficult airway, routine intubation is performed using DL in the sniffing position. The management of patients with UDA is conducted according to a specific institutional protocol. In appropriate cases where mask ventilation and oxygenation can be maintained, a hyper-angulated C-MAC® D-Blade videolaryngoscope (Karl Storz, Tuttlingen, Germany) is used as a rescue technique in patients who cannot be intubated using DL. If tracheal intubation cannot be achieved with videolaryngoscopy or other methods and the patient is awakened, and if the surgical procedure still requires general anesthesia, awake intubation using fiberoptic bronchoscopy (FOB) is planned.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18 to 90 years
  • Patients with unanticipated difficult airway

Exclusion criteria

  • Patients with missing data
  • Patients with a history of difficult airway
  • Patients with signs of difficult airway on preoperative evaluation

Treatment and study plan

Primary outcomes

  1. Intubation success

    Time frame: From anesthesia induction until the attempt of intubation is completed (peri-induction period).

    Successful intubation rate with DL or VL in patients with unpredictable difficult airway

Sponsors and collaborators

Lead sponsor

Tokat Gaziosmanpasa University

Other

Registry information

Official study title

Should Videolaryngoscopy Enter Routine Use? Unanticipated Difficult Airway: A Five-Year Experience in a Tertiary Care Hospital

Important dates

Study start
2020
Primary completion
2025
Study completion
2025
First posted
May 15, 2025
Registry last updated
May 16, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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