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Completed

NCT Number: NCT02785848

Identifying Barriers and Strategies to Support Self-efficacy for Medication Adherence With Text Messaging

The investigators will explore barriers to improving self-efficacy, or the ability to feel in control of their disease, and medication adherence with text messaging through surveys and interviews with adolescents and adults with SCD cared for at the Vanderbilt Meharry Center of Excellence (VMCE) in Sickle Cell Disease (SCD). The investigators will identify preferences to improve and sustain adherence to daily medication through selection of investigator-proposed or patient-generated text messaging strategies. Finally, the investigators will fill in the literature gaps by describing barriers to self-efficacy and medication adherence among adults with SCD as well as adolescents with SCD who are transitioning to adult care.

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Key information

Conditions

Sickle Cell Disease Anemia Anemia, Hemolytic Anemia, Hemolytic, Congenital Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities Genetic Diseases, Inborn Hematologic Diseases Hemic and Lymphatic Diseases Hemoglobinopathies

Age range

12 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Vanderbilt University

Nashville, Tennessee, 37203, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Receiving care at the VUMC/Matthew Walker clinic
  • Diagnosed with SCD, asthma, or both
  • Currently taking daily medications for SCD, such as hydroxyurea, asthma, or both
  • Having access to a mobile telephone and/or computer
  • Age 12-70 years

Exclusion criteria

  • Unable to perform interviews or surveys

Treatment and study plan

Interviews and Surveys

Other

The investigators will perform semi-structured interviews and surveys on this cohort

Primary outcomes

  1. Number of patients with barriers to medication adherence

    Time frame: 1 year

    High cost, forgetting, side effects, access to medications

Secondary outcomes

  1. Number of patients that prefer a tailored text messaging technological solution

    Time frame: 1 year

Sponsors and collaborators

Lead sponsor

Vanderbilt University

Other

Registry information

Official study title

Identifying Patient-centered Barriers and Preferred Strategies to Support Self-efficacy for Medication Adherence With Two-way Text Messaging

Important dates

Study start
2016
Primary completion
2022
Study completion
2026
First posted
May 30, 2016
Registry last updated
Sep 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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