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Clinical trial condition

Hemoglobinopathies

Explore clinical trials studying Hemoglobinopathies. Study availability and eligibility vary by location and protocol.

1,054 public trials 171 recruiting studies
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Hemoglobinopathies trial results

Recruiting

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

NCT07187973

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +7 more
Locations
  • University of Alabama at Birmingham Birmingham, Alabama, United States
  • Emory University Atlanta, Georgia, United States
  • Augusta University Augusta, Georgia, United States
  • Innovative Hematology - Indiana Hemophilia & Thrombosis Center Indianapolis, Indiana, United States
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Recruiting

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

NCT06439082

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +9 more
Locations
  • University Of Alabama Birmingham, Alabama, United States
  • Ctr for Inherited Blood Disorders Orange, California, United States
  • Childrens National Hospital Washington D.C., District of Columbia, United States
  • University of Florida Jacksonville, Florida, United States
View all 34 locations
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Recruiting

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

NCT05431088

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +7 more
Locations
  • Smilow Cancer Hospital New Haven, Connecticut, United States
  • Pediatric Hematology / Oncology a division of Kidz Medical services West Palm Beach, Florida, United States
  • St. Mary's Medical Center West Palm Beach, Florida, United States
  • Alpha Clinical Research Georgia Dunwoody, Georgia, United States
View all 80 locations
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Recruiting

Natural History of Sickle Cell Disease

NCT00081523

Conditions
Acute Chest Syndrome, Anemia, Anemia, Hemolytic, +15 more
Locations
  • Childrens National Health Center Washington D.C., District of Columbia, United States
  • Suburban Hospital Bethesda, Maryland, United States
  • National Institutes of Health Clinical Center Bethesda, Maryland, United States
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Recruiting

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

NCT06481306

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +7 more
Locations
  • University of Alabama at Birmingham Birmingham, Alabama, United States
  • University of California San Diego - La Jolla La Jolla, California, United States
  • UCSF Benioff Children's Hospital Oakland Oakland, California, United States
  • Yale-New Haven Hospital New Haven, Connecticut, United States
View all 32 locations
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Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

NCT04398628

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +34 more
Locations
  • Arizona Hemophilia and Thrombosis Treatment Center at Phoenix Children's Hospital Phoenix, Arizona, United States
  • Arkansas Center for Bleeding Disorders Little Rock, Arkansas, United States
  • Orthopaedic Institute for Children HTC Los Angeles, California, United States
  • Childrens Hospital Los Angeles Los Angeles, California, United States
View all 76 locations
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Recruiting

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

NCT06699849

Conditions
Acute Chest Syndrome, Acute Kidney Injury, Anemia, +20 more
Locations
  • Univ. of California, San Francisco Health Care Oakland, California, United States
  • University of California Irvine Orange, California, United States
  • Golisano Children's Hospital Fort Myers, Florida, United States
  • The Foundation for Sickle Cell Disease Hollywood, Florida, United States
View all 26 locations
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