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Clinical trial condition

Sickle Cell Disease

Explore clinical trials studying Sickle Cell Disease. Study availability and eligibility vary by location and protocol.

620 public trials 128 recruiting studies
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Sickle Cell Disease trial results

Recruiting

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

NCT07187973

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +7 more
Locations
  • University of Alabama at Birmingham Birmingham, Alabama, United States
  • Emory University Atlanta, Georgia, United States
  • Augusta University Augusta, Georgia, United States
  • Innovative Hematology - Indiana Hemophilia & Thrombosis Center Indianapolis, Indiana, United States
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Recruiting

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

NCT06439082

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +9 more
Locations
  • University Of Alabama Birmingham, Alabama, United States
  • Ctr for Inherited Blood Disorders Orange, California, United States
  • Childrens National Hospital Washington D.C., District of Columbia, United States
  • University of Florida Jacksonville, Florida, United States
View all 34 locations
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Recruiting

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

NCT05431088

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +7 more
Locations
  • Smilow Cancer Hospital New Haven, Connecticut, United States
  • Pediatric Hematology / Oncology a division of Kidz Medical services West Palm Beach, Florida, United States
  • St. Mary's Medical Center West Palm Beach, Florida, United States
  • Alpha Clinical Research Georgia Dunwoody, Georgia, United States
View all 80 locations
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Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

NCT04398628

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +34 more
Locations
  • Arizona Hemophilia and Thrombosis Treatment Center at Phoenix Children's Hospital Phoenix, Arizona, United States
  • Arkansas Center for Bleeding Disorders Little Rock, Arkansas, United States
  • Orthopaedic Institute for Children HTC Los Angeles, California, United States
  • Childrens Hospital Los Angeles Los Angeles, California, United States
View all 76 locations
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Recruiting

Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype

NCT07282210

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +9 more
Locations
  • The Hospital for Sick Children Toronto, Ontario, Canada
  • University Health Network, Toronto General Hospital Toronto, Ontario, Canada
  • Centre Hospitalier de l'Université de Montréal (CHUM) Montreal, Quebec, Canada
  • McGill University Health Centre Montreal, Quebec, Canada
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Recruiting

A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease

NCT06198712

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +7 more
Locations
  • The Hospital for Sick Children Toronto, Ontario, Canada
  • APHP - Centre de Référence des Syndromes Paris, France
  • Centre Hospitalier Universitaire de Rouen-Hopital Charles Nicolle Roeun, France
  • KEMRI-Walter-Reed Kericho Kericho, Kenya
View all 18 locations
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