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Clinical trial condition

TDP-43 Proteinopathies

Explore clinical trials studying TDP-43 Proteinopathies. Study availability and eligibility vary by location and protocol.

870 public trials 211 recruiting studies
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TDP-43 Proteinopathies trial results

Active, Not Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

NCT05262023

Conditions
Brain Diseases, Central Nervous System Diseases, Dementia, +10 more
Locations
  • University of California San Francisco San Francisco, California, United States
  • John Hopkins University Baltimore, Maryland, United States
  • Hospital of the University of Pennsylvania Philadelphia, Pennsylvania, United States
  • University of Antwerp Antwerp, Belgium
View all 26 locations
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Active, Not Recruiting

ALS Phase II Study of NX210c

NCT06365216

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Centre Hospitalier Regional Et Universitaire De Brest Brest, France
  • Centre Hospitalier Universitaire De Caen Normandie Caen, France
  • Hôpital La Timone - APHM Marseille, France
  • CHRU De Nancy Nancy, France
View all 16 locations
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Active, Not Recruiting

An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS

NCT05299658

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • Concord Hospital Concord, New South Wales, Australia
  • Neuroscience Research Australia Randwick, New South Wales, Australia
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