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Clinical trial condition

TDP-43 Proteinopathies

Explore clinical trials studying TDP-43 Proteinopathies. Study availability and eligibility vary by location and protocol.

870 public trials 211 recruiting studies
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TDP-43 Proteinopathies trial results

Recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

NCT06351592

Conditions
Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +10 more
Locations
  • Concord Repatriation General Hospital Concord, New South Wales, Australia
  • Macquarie University Sydney, New South Wales, Australia
  • Sunshine Coast University Hospital Birtinya, Queensland, Australia
  • KU Leuven Leuven, Vlaams-Brabant, Belgium
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Recruiting

AV-1980R (Tau Vaccine) in Preclinical Alzheimer's Disease (TAURUS-1980)

NCT07158905

Conditions
Alzheimer Disease, Brain Diseases, Central Nervous System Diseases, +16 more
Locations
  • Comprehensive Center for Brain Health Boca Raton, Florida, United States
  • Palm Springs Community Health Center Miami Lakes, Florida, United States
  • Alzheimer's Research and Treatment Center (Stuart) Stuart, Florida, United States
  • University of South Florida Tampa, Florida, United States
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Recruiting

HD-tDCS in Amyotrophic Lateral Sclerosis: A Multicenter Randomized Controlled Trial

NCT06719947

Conditions
Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +9 more
Locations
  • Universidade de Brasília - Campus Ceilândia Brasília, Federal District, Brazil
  • PneumoCardioVascular Lab - HUOL/UFRN Natal, Rio Grande do Norte, Brazil
  • Universidad Autónoma de Chile Santiago, Santiago Metropolitan, Chile
  • Universidad do Chile Santiago, Santiago Metropolitan, Chile
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Recruiting

A Substudy of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis

NCT07571174

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • UZ Leuven Leuven, Belgium
  • University Hospital - London Health Sciences Centre London, Canada
  • McGill University Health Centre Montreal, Canada
  • Sunnybrook Research Institute Toronto, Canada
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Recruiting

A Master Protocol (OLMP): A Study of LY4256984 in Participants With Amyotrophic Lateral Sclerosis (ALS)

NCT07571200

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • UZ Leuven Leuven, Belgium
  • University Hospital - London Health Sciences Centre London, Canada
  • McGill University Health Centre Montreal, Canada
  • Sunnybrook Research Institute Toronto, Canada
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Recruiting

A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)

NCT07290062

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • USA004 La Jolla, California, United States
  • USA002 Palo Alto, California, United States
  • USA001 Columbia, Missouri, United States
  • USA007 Columbus, Ohio, United States
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