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TDP-43 Proteinopathies

Clinical trial condition

TDP-43 Proteinopathies

Explore clinical trials studying TDP-43 Proteinopathies. Study availability and eligibility vary by location and protocol.

870 public trials 211 recruiting studies

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TDP-43 Proteinopathies trial results

Not Yet Recruiting

Healey ALS MyMatch Common Screening Protocol

NCT07400393

Conditions: ALS, ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis, +11 more
Locations: Not specified

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Kamlanoflast In Amyotrophic Lateral Sclerosis

NCT07396818

Conditions: ALS, ALS (Amyotrophic Lateral Sclerosis), Amyotrophic Lateral Sclerosis, +13 more
Locations: Not specified

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Not Yet Recruiting

MND Together: Phase 1

NCT07393932

Conditions: Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, MND (Motor Neurone DIsease), +9 more
Locations: School of Medicine and Populational Health Sheffield, Yorkshire, United Kingdom

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This Study Evaluates the Safety, Target Engagement, and Preliminary Efficacy of Galunisertib (TGF-βR1/ALK5 Inhibitor)Combined With Nerandomilast (PDE4 Inhibitor) in GREM2-positive ALS, a Biomarker-defined Subgroup Hypothesized to Reflect Heightened TGF-β/SMAD-driven Astrocytic and Fibrotic Signaling

NCT07321860

Conditions: ALS (Amyotrophic Lateral Sclerosis), Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, +9 more
Locations: Not specified

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Resiliency Intervention for Patients With ALS and Their Care-Partners

NCT06968468

Conditions: Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +10 more
Locations: Massachusetts General Hospital Boston, Massachusetts, United States

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Augmented Reality BCI Longitudinal Study for Persons With ALS, Stroke, TBI and SCI Utilizing Cognixion + Apple Vision Pro

NCT07209943

Conditions: ALS (Amyotrophic Lateral Sclerosis), Amyotrophic Lateral Sclerosis, Brain Diseases, +22 more
Locations: Cognixion HQ Santa Barbara, California, United States

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Efficacy and Safety of Masitinib in Combination With SoC Versus Placebo in the Treatment of ALS Patients

NCT07174492

Conditions: Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +9 more
Locations: Aiginition Hospital Athens, Greece

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Polish Version Dyspnea in Amyotrophic Lateral Sclerosis

NCT07178574

Conditions: Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Dyspnea, +14 more
Locations: Not specified

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Not Yet Recruiting

Dynamic Impact of NIV on Diaphragmatic Ultrasound in Patients With Amyotrophic Lateral Sclerosis

NCT07170865

Conditions: Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +10 more
Locations: CHU Grenoble-Alpes Grenoble, Isère, France

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A Phase Ⅰ/Ⅱa Study of SNUG01 in Adult Subjects With ALS

NCT07169175

Conditions: Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +9 more
Locations: Massachusetts General Hospital Boston, Massachusetts, United States

Peking University Third Hospital Beijing, Beijing Municipality, China

Fujian Medical University Union Hospital Fuzhou, Fujian, China

Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou, Zhejiang, China

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