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Clinical trial condition

Severe Hemophilia A

Explore clinical trials studying Severe Hemophilia A. Study availability and eligibility vary by location and protocol.

28 public trials 6 recruiting studies
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Severe Hemophilia A trial results

Recruiting

Study of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein (FRSW107) as Prophylactic Treatment.

NCT07684898

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Tianjin, Tianjin Municipality, China
  • Fuyang Hospital, Affiliated to Anhui Medical University Fuyang, China
  • Fujian Medical University Union Hospital Fuzhou, China
  • Nanfang Hospital of Southern Medical University Guangzhou, China
View all 19 locations
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Recruiting

Study of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein (FRSW107) On-Demand Treatment

NCT07663903

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Tianjin, Tianjin Municipality, China
  • Fuyang Hospital, Affiliated to Anhui Medical University Fuyang, China
  • Fujian Medical University Union Hospital Fuzhou, China
  • Ganzhou People's Hospital Ganzhou, China
View all 24 locations
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Recruiting

A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.

NCT06703606

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Orthopaedic Institute for Children/Orthopaedic Hemophilia Treatment Center Los Angeles, California, United States
  • Brody School of Medicine at East Carolina University Greenville, North Carolina, United States
  • ECU Health Medical Center Greenville, North Carolina, United States
  • Nirmal Hospital Pvt Ltd. Surat, Gujarat, India
View Trial Details
Recruiting

Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study

NCT05935358

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • UT Southwestern Medical Center Dallas, Texas, United States
  • University Hospital Centre Zagreb Zagreb, Croatia
  • Helsinki University Hospital Helsinki, Finland
  • CHU de Nantes Hôtel-Dieu Nantes, France
View all 18 locations
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Recruiting

Phase 3 Clinical Project of Pegylated Recombinant Human Coagulation Factor VIII-Fc Fusion Protein

NCT06142552

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Beijing tongren hospital,CMU Beijing, China
  • XiangYa Hospital CentralSouth University Changsha, China
  • The Second Affiliated Hospital of Chongqing Medical University Chongqing, China
  • Fujian Medical University Union Hospital Fuzhou, China
View all 28 locations
View Trial Details
Not yet recruiting

Study of Efficacy and Safety of FRSW107 in Pediatric Patients With Severe Hemophilia A

NCT06136507

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Children's Hospital Affiliated to Chongqing Medical University Chongqing, China
  • Guangzhou Women and Children Medical Center Guangzhou, China
  • Nanfang Hospital, Southern Medical University Guangzhou, China
  • Affiliated Hospital of Guizhou Medical University Guizhou, China
View all 13 locations
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Active, not recruiting

A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis

NCT05181618

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +8 more
Locations
  • Orthopaedic Institute for Children Los Angeles, California, United States
  • University of Miami Medical Center Miami, Florida, United States
  • Oklahoma Children's Hospital ? Jimmy Everest Center Oklahoma City, Oklahoma, United States
  • Hospital das Clinicas - UNICAMP Campinas, São Paulo, Brazil
View all 28 locations
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Active, not recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors

NCT04431726

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Phoenix Children's Hospital Phoenix, Arizona, United States
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • University of Colorado Denver, Children's Hospital Aurora, Colorado, United States
  • Tulane University Health Sciences Center New Orleans, Louisiana, United States
View all 32 locations
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