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Clinical trial condition

Severe Hemophilia A

Explore clinical trials studying Severe Hemophilia A. Study availability and eligibility vary by location and protocol.

28 public trials 3 recruiting studies
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Severe Hemophilia A trial results

Completed

Phase 3 Clinical Project of Pegylated Recombinant Human Coagulation Factor VIII-Fc Fusion Protein

NCT06142552

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Beijing tongren hospital,CMU Beijing, China
  • XiangYa Hospital CentralSouth University Changsha, China
  • The Second Affiliated Hospital of Chongqing Medical University Chongqing, China
  • Fujian Medical University Union Hospital Fuzhou, China
View all 28 locations
View Trial Details
Completed

rFVIII-Fc (Produced by AryoGen Pharmed Co.) Pharmacokinetic Study

NCT06137092

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Seyed-Al-Shohada Hospital Isfahan, Iran
  • Sarvar Clinic Mashhad, Iran
  • Dastqeib Hospital Shiraz, Iran
  • Imam Khomeini Tehran, Iran
View Trial Details
Completed

A Study to Evaluate the Pharmacokinetics，Safety and Tolerability of PEG Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection

NCT04864743

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Nanfang Hospital of Southern Medical University Guangzhou, China
  • People's Hospital of Zhengzhou Zhengzhou, Henan, China
  • Jinan central hospital Jinan, Shandong, China
  • Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College. Tianjin, Tianjin Municipality, China
View Trial Details
Completed

A Study of Repeat Dosing of PEG Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection

NCT05265286

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • People'S Hospital of Zhengzhou Zhengzhou, Henan, China
  • Affiliated Hospital of Jiangnan University Wuxi, Jiangsu, China
  • The Affiliated Hospital of Qingdao University Qingdao, Shandong, China
  • People'S Hospital of Rizhao Rizhao, Shandong, China
View Trial Details
Completed

An Open-label Safety and Efficacy Study of Recombinant FVIII in Patients With Severe Hemophilia A

NCT02172950

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Study Site 8400213 San Diego, California, United States
  • Study Site 8400241 Aurora, Colorado, United States
  • Study Site 8400118 Hartford, Connecticut, United States
  • Study Site 8400116 Miami, Florida, United States
View all 64 locations
View Trial Details
Completed

Clinical Study to Investigate the PK, Efficacy, and Safety of Wilate in Patients With Severe Hemophilia A

NCT02954575

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Specialized Hospital for Active Treatment "Joan Pavel" Sofia, Bulgaria
  • National Haemophilia Centre Budapest, Hungary
  • Krakowskie Centrum Medyczne Krakow, Poland
  • Korczowski Bartosz Gabinet Lekarski Rzeszów, Poland
View Trial Details
Completed

Pharmacokinetics, Efficacy, Safety, and Immunogenicity of Wilate in Previously Treated Paediatric Patients With Severe Haemophilia A

NCT03376516

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Kirov SSC Hematology and Transfusiology Kirov, Russia
  • "National Children's Specialized Clinic "OKHMATDYT" Kyiv, Ukraine
  • "Western Ukrainian Specialized Children's Medical Center" Lviv, Ukraine
View Trial Details
Completed

Human Cell Line-derived Recombinant Factor VIII (Human-cl-rhFVIII) in Previously Untreated Patients

NCT01712438

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • UC Davis Sacramento, California, United States
  • All Children's Hospital St. Petersburg, Florida, United States
  • Harvard Children's Hospital Boston Boston, Massachusetts, United States
  • Republican Scientific Practical Center for Pediatric Oncology and Hematology Minsk, Belarus
View all 37 locations
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