Clinical trial condition

PNH

Explore clinical trials studying PNH. Study availability and eligibility vary by location and protocol.

14 public trials 1 recruiting study

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PNH trial results

Recruiting

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

NCT06449001

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +10 more
Locations: Research Site Saskatoon, Saskatchewan, Canada

Research Site Paris, France

Research Site Leeds, United Kingdom

Research Site London, United Kingdom

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Completed

Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Ravulizumab in Chinese Adults Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

NCT06578949

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +6 more
Locations: Research Site Beijing, China

Research Site Guangzhou, China

Research Site Hangzhou, China

Research Site Nantong, China

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Completed

Pegcetacoplan Long Term Safety and Efficacy Extension Study

NCT03531255

Conditions: PNH
Locations: University of Southern California Los Angeles, California, United States

Denver Health Medical Center Denver, Colorado, United States

Cancer Specialists of North Florida Jacksonville, Florida, United States

Lakes Research Miami, Florida, United States

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Completed

A Phase III Study to Evaluate the Efficacy and Safety of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Are Naive to Complement Inhibitor Therapy

NCT06799546

Conditions: PNH
Locations: The First Affiliated Hospital of Nanjing Medical University Nanjing, Jiangsu, China

The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, Zhejiang, China

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Completed

A Retrospective Non-Interventional Study to Evaluate the Impact of Eculizumab in Korean PNH Patients

NCT05337683

Conditions: PNH
Locations: Handok Seoul, South Korea

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Completed

Observational of PNH Type Cells in Korean Patients With Bone Marrow Failure Syndrome and Having Hemolytic PNH

NCT03460301

Conditions: PNH
Locations: Not specified

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Completed

Retrospective Chart Review Screening Algorithm to Assess the Prevalence of PNH-clones

NCT05884060

Conditions: Anemia, Anemia, Aplastic, Bone Marrow Diseases, +9 more
Locations: AZ Delta Roeselare, West-Vlaanderen, Belgium

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Completed

Open-label, Multiple Ascending Dose Study of Ravulizumab (ALXN1210) in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

NCT02605993

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +6 more
Locations: Clinical Trial Site Toronto, Ontario, Canada

Clinical Trial Site Lyon, Pierre-Bénite, France

Clinical Trial Site Lille, France

Clinical Trial Site Paris, France

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Completed

Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of a Single Ascending Dose (SAD) of CAN106 Administered Intravenously (IV) in Healthy Subjects

NCT05095168

Conditions: PNH
Locations: National University Hospital Singapore

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Completed

Dose-Escalation Study of ALXN1210 IV in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

NCT02598583

Conditions: Anemia, Anemia, Hemolytic, Bone Marrow Diseases, +5 more
Locations: Clinical Trial Site Liverpool, New South Wales, Australia

Clinical Trial Site Woolloongabba, Queensland, Australia

Clinical Trial Site Seoul, South Korea

Clinical Trial Site Seoul, South Korea

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PNH

PNH trial results

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