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Clinical trial condition

Neurofibromatosis Type 1

Explore clinical trials studying Neurofibromatosis Type 1. Study availability and eligibility vary by location and protocol.

59 public trials 5 recruiting studies
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Neurofibromatosis Type 1 trial results

Recruiting

A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)

NCT06507748

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +21 more
Locations
  • Children's National Medical Center Washington D.C., District of Columbia, United States
  • National Institutes of Health Clinical Center Bethesda, Maryland, United States
View Trial Details
Recruiting

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

NCT06541847

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +17 more
Locations
  • University of Alabama at Birmingham Birmingham, Alabama, United States
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • Stanford University Palo Alto, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
View all 14 locations
View Trial Details
Active, not recruiting

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN

NCT05309668

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Akron, Ohio, United States
  • Research Site Philadelphia, Pennsylvania, United States
  • Research Site Houston, Texas, United States
  • Research Site Richmond, Virginia, United States
View all 16 locations
View Trial Details
Active, not recruiting

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

NCT03871257

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +16 more
Locations
  • Children's Hospital of Alabama Birmingham, Alabama, United States
  • Banner Children's at Desert Mesa, Arizona, United States
  • Phoenix Childrens Hospital Phoenix, Arizona, United States
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
View all 132 locations
View Trial Details
Active, not recruiting

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

NCT01362803

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +22 more
Locations
  • Children's National Medical Center Washington D.C., District of Columbia, United States
  • National Institutes of Health Clinical Center Bethesda, Maryland, United States
  • Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States
  • Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States
View Trial Details

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