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Clinical trial condition

Neurofibromatosis Type 1

Explore clinical trials studying Neurofibromatosis Type 1. Study availability and eligibility vary by location and protocol.

59 public trials 6 recruiting studies
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Neurofibromatosis Type 1 trial results

Active, Not Recruiting

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

NCT01362803

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +22 more
Locations
  • Children's National Medical Center Washington D.C., District of Columbia, United States
  • National Institutes of Health Clinical Center Bethesda, Maryland, United States
  • Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States
  • Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States
View Trial Details
Active, Not Recruiting

Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

NCT03190915

Conditions
Bone Marrow Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +22 more
Locations
  • Children's Hospital of Alabama Birmingham, Alabama, United States
  • Phoenix Childrens Hospital Phoenix, Arizona, United States
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
  • Kaiser Permanente Downey Medical Center Downey, California, United States
View all 57 locations
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Active, Not Recruiting

Pediatric Long-Term Follow-up and Rollover Study

NCT03975829

Conditions
Anaplastic Astrocytoma, Anaplastic Ganglioglioma, Anaplastic Oligodendroglioma, +62 more
Locations
  • Phoenix Children s Hospital Phoenix, Arizona, United States
  • Childrens National Hospital Washington D.C., District of Columbia, United States
  • Nicklaus Childrens Hospital Miami, Florida, United States
  • Indiana Uni School of Medicine Indianapolis, Indiana, United States
View all 55 locations
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Active, Not Recruiting

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

NCT03871257

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +16 more
Locations
  • Children's Hospital of Alabama Birmingham, Alabama, United States
  • Banner Children's at Desert Mesa, Arizona, United States
  • Phoenix Childrens Hospital Phoenix, Arizona, United States
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
View all 132 locations
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Active, Not Recruiting

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN

NCT05309668

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Akron, Ohio, United States
  • Research Site Philadelphia, Pennsylvania, United States
  • Research Site Houston, Texas, United States
  • Research Site Richmond, Virginia, United States
View all 16 locations
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Active, Not Recruiting

Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas

NCT05101148

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Rochester, Minnesota, United States
  • Research Site Akron, Ohio, United States
  • Research Site Bydgoszcz, Poland
  • Research Site Gdansk, Poland
View Trial Details
Active, Not Recruiting

PASS of Paediatric Patients Initiating Selumetinib

NCT05388370

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Vienna, Austria
  • Research Site Amiens, France
  • Research Site Angers, France
  • Research Site Bordeaux, France
View all 46 locations
View Trial Details

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