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Neurofibromatosis 1

Clinical trial condition

Neurofibromatosis 1

Explore clinical trials studying Neurofibromatosis 1. Study availability and eligibility vary by location and protocol.

133 public trials 21 recruiting studies

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Neurofibromatosis 1 trial results

Recruiting

HL-085 in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

NCT05331105

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +17 more
Locations: Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine Shanghai, Shanghai Municipality, China

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Enrolling by Invitation

Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs)

NCT06300502

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +16 more
Locations: Wellman Center for Photomedicine Boston, Massachusetts, United States

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Enrolling by Invitation

Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1

NCT05238909

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States

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Not Yet Recruiting

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

NCT05253131

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Fibrosarcoma, Genetic Diseases, Inborn, +23 more
Locations: The University of Alabama at Birmingham Birmingham, Alabama, United States

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Not Yet Recruiting

Gait in Young Children With NF1

NCT07564622

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations: Not specified

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Not Yet Recruiting

Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma

NCT07521657

Conditions: Astrocytoma, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +21 more
Locations: Childrens of Alabama Birmingham, Alabama, United States

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Not Yet Recruiting

Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas

NCT06502171

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +17 more
Locations: University of Alabama at Birmingham Birmingham, Alabama, United States

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Not Yet Recruiting

iCanCope With NF: Innovating an Efficacious Digital Self-management and Transitional Care Program for Adolescents With Neurofibromatosis

NCT07077408

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +13 more
Locations: Not specified

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Not Yet Recruiting

Follow-up Study to Evaluate the Safety and Efficacy of FCN-159 in Pediatric Participants With Neurofibromatosis Type 1

NCT07024394

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +18 more
Locations: Shanghai Ninth People's Hospital Shanghai, Shanghai Municipality, China

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Not Yet Recruiting

Low-dose Selumetinib for the Treatment of Plexiform Neurofibromas in Chinese Children

NCT06763315

Conditions: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +17 more
Locations: West China Hospital of Sichuan University Chengdu, Sichuan, China

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Neurofibromatosis 1

Neurofibromatosis 1 trial results

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