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Clinical trial condition

Neurofibromatosis 1

Explore clinical trials studying Neurofibromatosis 1. Study availability and eligibility vary by location and protocol.

133 public trials 21 recruiting studies
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Neurofibromatosis 1 trial results

Active, Not Recruiting

NF-1, Nutraceutical Intervention

NCT05363267

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +13 more
Locations
  • Masonic Cancer Center, University of Minnesota Minneapolis, Minnesota, United States
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Active, Not Recruiting

Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas

NCT05101148

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Rochester, Minnesota, United States
  • Research Site Akron, Ohio, United States
  • Research Site Bydgoszcz, Poland
  • Research Site Gdansk, Poland
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Active, Not Recruiting

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

NCT01089101

Conditions
Astrocytoma, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +25 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • Lucile Packard Children's Hospital Stanford University Palo Alto, California, United States
  • UCSF Medical Center-Mount Zion San Francisco, California, United States
  • UCSF Medical Center-Parnassus San Francisco, California, United States
View all 17 locations
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Active, Not Recruiting

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

NCT03363217

Conditions
Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, +29 more
Locations
  • Alberta Children's Hospital Calgary, Alberta, Canada
  • Children and Women's Health Centre of British Colombia Vancouver, British Columbia, Canada
  • IWK Health Centre Halifax, Nova Scotia, Canada
  • The Hospital for Sick Children Toronto, Ontario, Canada
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Active, Not Recruiting

Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas

NCT04924608

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +17 more
Locations
  • Research Site Gainesville, Florida, United States
  • Research Site Rockville, Maryland, United States
  • Research Site St Louis, Missouri, United States
  • Research Site Commack, New York, United States
View all 34 locations
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Active, Not Recruiting

PASS of Paediatric Patients Initiating Selumetinib

NCT05388370

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Vienna, Austria
  • Research Site Amiens, France
  • Research Site Angers, France
  • Research Site Bordeaux, France
View all 46 locations
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