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Clinical trial condition

Muscular Atrophy, Spinal

Explore clinical trials studying Muscular Atrophy, Spinal. Study availability and eligibility vary by location and protocol.

214 public trials 48 recruiting studies
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Muscular Atrophy, Spinal trial results

Completed

Efficacy and Safety of Intrathecal OAV101 (AVXS-101) in Pediatric Patients With Type 2 Spinal Muscular Atrophy (SMA)

NCT05089656

Conditions
Atrophy, Central Nervous System Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +18 more
Locations
  • Connecticut Children's Medical Center Farmington, Connecticut, United States
  • Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
  • Clinic for Special Children Strasburg, Pennsylvania, United States
  • St Jude Children's Research Hospital Memphis, Tennessee, United States
View all 42 locations
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Completed

Newborn Screening for Spinal Muscular Atrophy

NCT05481164

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Buckinghamshire HealthCare Trust Buckingham, United Kingdom
  • Dorset County Hospital (DCHFT) Dorchester, United Kingdom
  • Milton Keynes University Hospital NHS Foundation Trust Milton Keynes, United Kingdom
  • University of Oxford UK Oxford, United Kingdom
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Completed

A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy

NCT02386553

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • David Geffen School of Medicine Los Angeles, California, United States
  • University of California Davis Health System Sacramento, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Nemours Children's Hospital, Orlando Orlando, Florida, United States
View all 21 locations
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Completed

A Study to Learn About the Effect of Nusinersen (BIIB058) Given as Injections to Children With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec (RESPOND)

NCT04488133

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Arkansas Children's Hospital Research Institute Little Rock, Arkansas, United States
  • Stanford Neuromuscular Research Palo Alto, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
View all 15 locations
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Completed

A Study of Risdiplam (RO7034067) in Adult and Pediatric Participants With Spinal Muscular Atrophy

NCT03032172

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Stanford University Medical Center Palo Alto, California, United States
  • Nemours Children's Hospital Orlando, Florida, United States
  • Boston Childrens Hospital Boston, Massachusetts, United States
  • Columbia University Medical Center New York, United States
View all 24 locations
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Completed

Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy

NCT04089566

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Stanford Hospital and Clinics Palo Alto, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
  • The Johns Hopkins Hospital Baltimore, Maryland, United States
View all 45 locations
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