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Completed

NCT Number: NCT00961103

Motor Development and Orthoses in Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA) is neurodegenerative disease of anterior horn cells of spinal cord and represents the second more frequent pathology in childhood.

According to the age of onset and the maximum motor function the disorder is classified in 4 types. Patients with SMA II and SMA III often use orthoses to achieve postural and dynamic functions.

In this retrospective observational study the investigators describe the characteristics of sitting position, standing and walking correlated to type and time of orthoses used.

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Key information

Conditions

Spinal Muscular Atrophy Central Nervous System Diseases Motor Neuron Disease Muscular Atrophy, Spinal Nervous System Diseases Neurodegenerative Diseases Neuromuscular Diseases Spinal Cord Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

UDGEE Hospital S.Maria Nuova

Reggio Emilia, RE, 42100, Italy

About this study

We collect data from patients with SMA II and SMA III referred to UDGEE from jan. 1995 to dec. 2008.

We estimate to achieve informations about 50-70 patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical and genetics diagnosis of SMA II and SMA III

Exclusion criteria

  • N/A

Treatment and study plan

Primary outcomes

  1. time and percentage of sitting, standing, walking achievement in SMA II and SMA III

    Time frame: aug.2009- nov.2009

Secondary outcomes

  1. characteristics and percentage of orthoses for postural sitting control , standing and walking in SMA II and SMA III

    Time frame: aug. 2009 - dec.2009

Sponsors and collaborators

Lead sponsor

Azienda USL Reggio Emilia - IRCCS

Other Gov

Registry information

Official study title

Assessment of Motor Development Related to Use of Orthoses in SMA II and III

Important dates

Study start
2009
Primary completion
2009
Study completion
2011
First posted
Aug 18, 2009
Registry last updated
Dec 23, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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