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Clinical trial condition

Muscular Atrophy, Spinal

Explore clinical trials studying Muscular Atrophy, Spinal. Study availability and eligibility vary by location and protocol.

41 public trials 7 recruiting studies
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Muscular Atrophy, Spinal trial results

Recruiting

A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

NCT07221669

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Ann and Robert H Lurie Childrens Hospital of Chicago Chicago, Illinois, United States
  • Neurology Rare Disease Center Flower Mound, Texas, United States
  • Childrens Hospital of the Kings Daughter Norfolk Norfolk, Virginia, United States
  • Childrens Hospital of Fudan University_Shanghai Shanghai, China
View Trial Details
Recruiting

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

NCT05861999

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • University of Arkansas for Medical Sciences Little Rock, Arkansas, United States
  • Valley Children's Hospital Madera, California, United States
  • Stanford Univ Medical Center Palo Alto, California, United States
  • Children's Hospital of Colorado Aurora, Colorado, United States
View all 19 locations
View Trial Details
Recruiting

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

NCT05861986

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • University of Arkansas for Medical Sciences Little Rock, Arkansas, United States
  • Children's Hospital of Colorado Aurora, Colorado, United States
  • University of Florida Pediatrics Gainesville, Florida, United States
  • Children's Healthcare of Atlanta Center for Advanced Pediatrics Atlanta, Georgia, United States
View all 16 locations
View Trial Details
Recruiting

A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)

NCT06555419

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Children's Hospital of Orange County Orange, California, United States
  • Stanford University Medical Center | Department of Neurology_Palo Alto Palo Alto, California, United States
  • Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
  • Boston Children's Hospital Boston, Massachusetts, United States
View all 19 locations
View Trial Details
Recruiting

A Study to Learn How Nusinersen (Spinraza) Affects Participants With Spinal Muscular Atrophy (SMA) Who Took it Before or During Pregnancy And About The Health of Their Babies

NCT05789758

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Stanford Neuroscience Health Center Palo Alto, California, United States
  • Boston Children's Hospital Boston, Massachusetts, United States
  • Research Site Cambridge, Massachusetts, United States
  • Columbia University Irving Medical Center New York, United States
View all 14 locations
View Trial Details
Recruiting

Natural History of SMA

NCT05755451

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Istituto Gaslini Genova, Italy
  • Nemo Sud Messina, Italy
  • Centro Clinico nemo Milan, Italy
  • Ospedale Bambino gesu Rome, Italy
View Trial Details
Active, not recruiting

Adult Spinal Muscular Atrophy (SMA) China Registry

NCT05618379

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Peking Union Medical College Hospital Beijing, Beijing Municipality, China
  • The First Affiliated Hospital of Fujian Medical University Fuzhou, Fujian, China
  • The First Affiliated Hospital, Sun Yat-sen University Guangzhou, Guangdong, China
  • Peking University Shenzhen Hospital Shenzhen, Guangdong, China
View Trial Details
Active, not recruiting

Observational, Postmarketing Surveillance Study of Spinraza Injection (Nusinersen Sodium)

NCT04317794

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Pusan Natioanl University Hospital Busan, South Korea
  • Samsung Changwon Hospital Changwon, South Korea
  • Chungbuk National University Hospital Cheongju-si, South Korea
  • Kyungpook National University Hospital Daegu, South Korea
View all 16 locations
View Trial Details
Active, not recruiting

A Study of Risdiplam in Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy

NCT03779334

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Nemours Children's Hospital Orlando, Florida, United States
  • Sydney Children's Hospital Randwick, New South Wales, Australia
  • Chr de La Citadelle Liège, Belgium
  • Hospital das Clinicas - FMUSP_X São Paulo, Brazil
View Trial Details

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