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Clinical trial condition

Muscular Atrophy, Spinal

Explore clinical trials studying Muscular Atrophy, Spinal. Study availability and eligibility vary by location and protocol.

41 public trials 6 recruiting studies
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Muscular Atrophy, Spinal trial results

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants

NCT02908685

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Stanford University Medical Center Palo Alto, California, United States
  • Columbia University Medical Center; The Neurological Institute of New York New York, United States
  • UZ Gent Ghent, Belgium
  • UZ Leuven Gasthuisberg Leuven, Belgium
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Completed

Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants

NCT04718181

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Daytona Beach Clinical Rsch Unit Daytona Beach, Florida, United States
  • QPS- Springfield Springfield, Missouri, United States
  • Dallas Clinical Research Unit Dallas, Texas, United States
  • Covance Clinical Research Unit, Inc Madison, Wisconsin, United States
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Completed

A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics and Safety and Tolerability of a Single Oral Dose of Risdiplam Compared to Matched Healthy Participants With Normal Hepatic Function

NCT03920865

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • Clinical Pharmacology of Miami, Inc. Miami, Florida, United States
  • Orlando Clinical Research Center Orlando, Florida, United States
  • American Research Corporation Inc. San Antonio, Texas, United States
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Completed

A Study to Evaluate Long Term Safety, Tolerability, and Effectiveness of Olesoxime in Patients With Spinal Muscular Atrophy (SMA)

NCT02628743

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • UZ Gent Ghent, Belgium
  • UZ Leuven Gasthuisberg Leuven, Belgium
  • Hopital Femme Mere Enfant; Medecine Physique et Readaptation Pediatrique - L'ESCALE Bron, France
  • Hôpital Raymond Poincare; Serv. Neurologie et Réanimation pédiatriques - Centre réf. neuromusculaire Garches, France
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