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Clinical trial condition

Motor Neuron Disease

Explore clinical trials studying Motor Neuron Disease. Study availability and eligibility vary by location and protocol.

839 public trials 197 recruiting studies
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Motor Neuron Disease trial results

Completed

Gene Replacement Therapy Clinical Trial for Participants With Spinal Muscular Atrophy Type 1

NCT03306277

Conditions
Central Nervous System Diseases, Gene Therapy, Motor Neuron Disease, +6 more
Locations
  • David Geffen School of Medicine at UCLA Los Angeles, California, United States
  • Stanford University Stanford, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Nemours Children's Hospital Orlando, Florida, United States
View all 16 locations
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Completed

Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam

NCT05156320

Conditions
Anti-myostatin, Atrophy, Central Nervous System Diseases, +20 more
Locations
  • Children's of Alabama Birmingham, Alabama, United States
  • Phoenix Children's Hospital Phoenix, Arizona, United States
  • Children's Hospital of Los Angeles Los Angeles, California, United States
  • Stanford University Medical Center Palo Alto, California, United States
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Completed

Phase IIIb, Open-label, Multi-center Study to Evaluate Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally to Participants With SMA Who Discontinued Treatment With Nusinersen or Risdiplam

NCT05386680

Conditions
Atrophy, Bulbo-Spinal Atrophy, X-Linked, Central Nervous System Diseases, +19 more
Locations
  • Boston Childrens Hospital Boston, Massachusetts, United States
  • Child Hosp Of The Kings Daughters Norfolk, Virginia, United States
  • University of Wisconsin Madison Medical School Madison, Wisconsin, United States
  • Novartis Investigative Site Parkville, Victoria, Australia
View all 13 locations
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Completed

Efficacy and Safety of Intrathecal OAV101 (AVXS-101) in Pediatric Patients With Type 2 Spinal Muscular Atrophy (SMA)

NCT05089656

Conditions
Atrophy, Central Nervous System Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +18 more
Locations
  • Connecticut Children's Medical Center Farmington, Connecticut, United States
  • Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
  • Clinic for Special Children Strasburg, Pennsylvania, United States
  • St Jude Children's Research Hospital Memphis, Tennessee, United States
View all 42 locations
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