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Clinical trial condition

Homozygous Familial Hypercholesterolemia (HoFH)

Explore clinical trials studying Homozygous Familial Hypercholesterolemia (HoFH). Study availability and eligibility vary by location and protocol.

9 public trials 4 recruiting studies
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Homozygous Familial Hypercholesterolemia (HoFH) trial results

Recruiting

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

NCT07491172

Conditions
Cardiovascular, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, +20 more
Locations
  • Integrity Clinical Research Hialeah, Florida, United States
  • Jacksonville Center for Clinical Research Jacksonville, Florida, United States
  • Flourish Orlando Orlando, Florida, United States
  • United Medical Research Port Orange, Florida, United States
View all 19 locations
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Recruiting

Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

NCT07447648

Conditions
Arterial Occlusive Diseases, Arteriosclerosis, Atherosclerosis, +16 more
Locations
  • Unité de Lipidologie et Prévention Cardiovasculaire, Centre de Compétence Dyslipidémies Rares (CEDRA), Service de Nutrition, Hôpital Pitié-Salpétriêre Paris, France
  • Dipartimento Scienze-Cardiovascolari, AO "Sant'Anna e San Sebastiano" di Caserta Caserta, Italy
  • U.O.C. di Medicina Interna, P.O. Nesima, ARNAS Garibaldi Catania, Italy
  • Nefrologia e Emodialisi, Centro Aterosclerosi e Dislipidemie, Ospedale Bassini, ASST Nord Milano Cinisello Balsamo, Italy
View all 13 locations
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Recruiting

The ORIGIN-FH Study

NCT07470723

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Familial Hypercholesterolemia, +12 more
Locations
  • University of Wisconsin - Madison Madison, Wisconsin, United States
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Completed

A Study to Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

NCT02434497

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Genetic Diseases, Inborn, +10 more
Locations
  • Research Site Brussels (Woluwé-St-Lambert), Belgium
  • Research Site Chicoutimi, Quebec, Canada
  • Research Site Copenhagen, Denmark
  • Research Site Halfa, Israel
View Trial Details
Completed

A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

NCT02226198

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyslipidemias, Genetic Diseases, Inborn, +10 more
Locations
  • Research Site Brussels (Woluwé-St-Lambert), Belgium
  • Research Site Chicoutimi, Quebec, Canada
  • Research Site København Ø, Denmark
  • Research Site Haifa, Israel
View Trial Details
Active, Not Recruiting

Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial Hypercholesterolemia

NCT06832371

Conditions
Arterial Occlusive Diseases, Arteriosclerosis, Atherosclerosis, +18 more
Locations
  • CHRU Lille - Centre Hospitalier Universitaire de Lille Lille, France
  • Centre Hospitalier Universitaire de Lyon (CHU Lyon) Lyon, France
  • Hôpital de la Conception - Assistance Publique Hôpitaux de Marseille (AP-HM) Marseille, France
  • Hôpital La Pitié Salpêtrière - Groupe Hospitalier "La Pitié Salpêtrière - Charles Foix" Paris, France
View all 30 locations
View Trial Details

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