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Clinical trial condition

Heredodegenerative Disorders, Nervous System

Explore clinical trials studying Heredodegenerative Disorders, Nervous System. Study availability and eligibility vary by location and protocol.

1,876 public trials 411 recruiting studies
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Heredodegenerative Disorders, Nervous System trial results

Active, Not Recruiting

A Study to Evaluate the Safety and Efficacy of Zilganersen (ION373) in Patients With Alexander Disease (AxD)

NCT04849741

Conditions
Alexander Disease, Brain Diseases, Brain Diseases, Metabolic, +13 more
Locations
  • Lucile Packard Children's Hospital Stanford Palo Alto, California, United States
  • Children's Hospital of Atlanta Atlanta, Georgia, United States
  • Massachusetts General Hospital Boston, Massachusetts, United States
  • Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States
View all 13 locations
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Active, Not Recruiting

Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment

NCT02962414

Conditions
Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +17 more
Locations
  • TGen APNNA Phoenix, Arizona, United States
  • David Geffen School of Medicine at UCLA Los Angeles, California, United States
  • UCSF Benioff Children s Hospital Oakland, California, United States
  • Rady Children s Hospital San Diego, California, United States
View all 68 locations
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Active, Not Recruiting

Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

NCT06392009

Conditions
Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Focal Cortical Dysplasia, +14 more
Locations
  • Queensland Children Hospital South Brisbane, Australia
  • University Hospitals Leuven, Pediatric Neurology Leuven, Belgium
  • Alberta Children's Hospital Calgary, Canada
  • The Hospital for Sick Children (Sick Kids) Toronto, Canada
View all 18 locations
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Active, Not Recruiting

Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas

NCT04924608

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +17 more
Locations
  • Research Site Gainesville, Florida, United States
  • Research Site Rockville, Maryland, United States
  • Research Site St Louis, Missouri, United States
  • Research Site Commack, New York, United States
View all 34 locations
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Active, Not Recruiting

PASS of Paediatric Patients Initiating Selumetinib

NCT05388370

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Vienna, Austria
  • Research Site Amiens, France
  • Research Site Angers, France
  • Research Site Bordeaux, France
View all 46 locations
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