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Clinical trial condition

Hemophilia B

Explore clinical trials studying Hemophilia B. Study availability and eligibility vary by location and protocol.

205 public trials 28 recruiting studies
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Hemophilia B trial results

Recruiting

Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

NCT06003387

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • University of California, San Diego (UCSD) San Diego, California, United States
  • University of Michigan Ann Arbor, Michigan, United States
  • Hemophilia Center of Western Pennsylvania (HCWP) Pittsburgh, Pennsylvania, United States
  • Royal Prince Alfred Hospital Camperdown, New South Wales, Australia
View all 30 locations
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Recruiting

Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

NCT07080905

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Center for Inherited Blood Disorders Orange, California, United States
  • University of Florida Gainesville, Florida, United States
  • Arthur M. Blank Hospital - Children's Healthcare of Atlanta Atlanta, Georgia, United States
  • University of Michigan Medical Center Ann Arbor, Michigan, United States
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Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

NCT04398628

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +34 more
Locations
  • Arizona Hemophilia and Thrombosis Treatment Center at Phoenix Children's Hospital Phoenix, Arizona, United States
  • Arkansas Center for Bleeding Disorders Little Rock, Arkansas, United States
  • Orthopaedic Institute for Children HTC Los Angeles, California, United States
  • Childrens Hospital Los Angeles Los Angeles, California, United States
View all 71 locations
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Recruiting

A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B

NCT06379789

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +7 more
Locations
  • Orthopaedic Hemophilia Treatment Center Los Angeles, California, United States
  • David Geffen School of Medicine at UCLA Los Angeles, California, United States
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • University of California Davis Sacramento, California, United States
View all 44 locations
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Recruiting

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)

NCT06349473

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +10 more
Locations
  • California Clinical Trials Medical Group (CCTMG) Glendale, California, United States
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • Rush University Medical Center Chicago, Illinois, United States
  • LA Center for Bleeding and Clotting Disorders - Metairie Metairie, Louisiana, United States
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Recruiting

An Open-label, Multicenter Phase I/II Clinical Trial to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic/Pharmacodynamic (PK/PD) Characteristics of SR604 Injection in Patients With Hemophilia A/B and Congenital Factor VII Deficiency

NCT07644832

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +9 more
Locations
  • Xiangya Hospital of Central South University Changsha, China
  • The First Affiliated Hospital of University of Science and Technology of China Hefei, China
  • Jinan Central Hospital Jinan, China
  • The First Hospital of Lanzhou University Lanzhou, China
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Recruiting

Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively

NCT05568719

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +11 more
Locations
  • The Regents of the University of California||UC Davis Health Rancho Cordova, California, United States
  • UC Davis Health Sacramento, California, United States
  • UC Davis Ambulatory Care Clinic Sacramento, California, United States
  • UC Davis Hemophilia Treatment Center Sacramento, California, United States
View all 23 locations
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Recruiting

A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

NCT05611801

Conditions
Blood Coagulation Disorders, Blood Coagulation Disorders, Inherited, Coagulation Protein Disorders, +11 more
Locations
  • Arbesu Hematología Mendoza, Argentina
  • Murdoch Children's Research Institute Parkville, Australia
  • Medizinische Universität Wien Vienna, State of Vienna, Austria
  • Hamilton Health Sciences - McMaster University Medical Centre Hamilton, Ontario/canada, Canada
View all 34 locations
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