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Clinical trial condition

beta-Thalassemia

Explore clinical trials studying beta-Thalassemia. Study availability and eligibility vary by location and protocol.

184 public trials 29 recruiting studies
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beta-Thalassemia trial results

Active, Not Recruiting

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)

NCT05356195

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +8 more
Locations
  • TriStar Medical Group Children's Specialists - Pediatric Oncology Nashville, Tennessee, United States
  • Hospital for Sick Children - Hematology Toronto, Canada
  • University Hospital Dusseldorf - Department of Pediatric Oncology, Hematology and Clinical Immunology Düsseldorf, Germany
  • IRCSS Ospedale Pediatrico Bambino Gesu - Dipartimento di Onco-Ematologia e Terapia Cellulare e Genica Rome, Italy
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Active, Not Recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

NCT06421636

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +8 more
Locations
  • Weill Cornell Medicine New York, United States
  • K Eristavi National Center of Experimental and Clinical Surgery Tbilisi, Georgia
  • Medinvest Institute of Hematology and Transfusiology Limited Tbilisi, Georgia
  • Children's Hospital Agia Sophia Athens, Attica, Greece
View all 26 locations
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Active, Not Recruiting

A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001)

NCT05353647

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +9 more
Locations
  • Children's Hospital of Los Angeles Los Angeles, California, United States
  • UCLA Medical Center Los Angeles, California, United States
  • UCSF Benioff Children's Hospital Oakland Oakland, California, United States
  • UC Davis Medical Center Sacramento, California, United States
View Trial Details
Active, Not Recruiting

Gene Transfer for Sickle Cell Disease

NCT03282656

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +9 more
Locations
  • UCLA - Mattel Children's Hospital Los Angeles, California, United States
  • Boston Children's Hospital Boston, Massachusetts, United States
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Active, Not Recruiting

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

NCT05145062

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +10 more
Locations
  • UCSF Benioff Children's Hospital Oakland, California, United States
  • University of California Davis Health System Sacramento, California, United States
  • Children's Healthcare of Atlanta Atlanta, Georgia, United States
  • Boston Children's Hospital Boston, Massachusetts, United States
View Trial Details
Active, Not Recruiting

A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India

NCT05891249

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +8 more
Locations
  • Local Institution - 0002 Ahmedabad, Gujarat, India
  • Local Institution - 0001 New Delhi, National Capital Territory of Delhi, India
  • Local Institution - 0007 Kolkata, West Bengal, India
  • Local Institution - 0005 Assam, India
View Trial Details
Active, Not Recruiting

A Study to Evaluate Luspatercept (ACE-536) in Chinese Participants Who Require Regular Red Blood Cell Transfusions Due to Beta (β)-Thalassemia.

NCT05567458

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +8 more
Locations
  • Local Institution - 0002 Maoming, Guangdong, China
  • Local Institution - 0005 Shenzhen, Guangdong, China
  • Local Institution - 0007 Liuzhou, Guangxi, China
  • Local Institution - 0003 Nanning, GX, China
View Trial Details

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