Skip to main content
OpenTrials

Clinical trial condition

Alpha 1-Antitrypsin Deficiency

Explore clinical trials studying Alpha 1-Antitrypsin Deficiency. Study availability and eligibility vary by location and protocol.

33 public trials 5 recruiting studies
Refine in advanced search Browse all conditions

Alpha 1-Antitrypsin Deficiency trial results

Recruiting

Alpha-1 Research Registry

NCT04157049

Conditions
Alpha 1-Antitrypsin Deficiency, Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +13 more
Locations
  • Alpha-1 Foundation Coral Gables, Florida, United States
View Trial Details
Recruiting

A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)

NCT06389877

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Clinical Study Center Birmingham, Alabama, United States
  • Clinical Study Center Boston, Massachusetts, United States
  • Clinical Study Center Charleston, South Carolina, United States
  • Clinical Study Center Adelaide, Australia
View Trial Details
Recruiting

PiMZ Longitudinal Cohort (PiMZ Logic)

NCT06505603

Conditions
Alpha 1-Antitrypsin Deficiency, Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +14 more
Locations
  • University of Alabama at Birmingham Birmingham, Alabama, United States
  • University of California- Los Angeles Los Angeles, California, United States
  • National Jewish Health Denver, Colorado, United States
  • University of Chicago Chicago, Illinois, United States
View Trial Details
Recruiting

A Study of KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency

NCT06049082

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • University of Florida, Gainesville Gainesville, Florida, United States
  • Medical University of South Carolina Charleston, South Carolina, United States
  • Renovatio Clinical The Woodlands, Texas, United States
View Trial Details
Active, not recruiting

Study of BMN 349 Single Dose in PiZZ and PiMZ/MASH Adult Participants

NCT06738017

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • University of California, San Diego San Diego, California, United States
  • Saint Louis University St Louis, Missouri, United States
  • Medpace Clinical Pharmacology Unit Cincinnati, Ohio, United States
  • The Medical University of South Carolina Charleston, South Carolina, United States
View Trial Details
Active, not recruiting

Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema

NCT05897424

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • UAB Lung Health Center- Site Number : 105 Birmingham, Alabama, United States
  • St Joseph's Hospital and Medical Center- Site Number : 126 Phoenix, Arizona, United States
  • David Geffen School of Medicine at UCLA- Site Number : 124 Los Angeles, California, United States
  • University of California Davis Medical Center- Site Number : 110 Sacramento, California, United States
View all 40 locations
View Trial Details
Active, not recruiting

Alpha-1 Antitrypsin Disease Cohort: Longitudinal Biomarker Study of Disease

NCT05297812

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +10 more
Locations
  • University of Alabama at Birmingham Birmingham, Alabama, United States
  • University of California - Los Angeles Los Angeles, California, United States
  • National Jewish Health Denver, Colorado, United States
  • University of Chicago Chicago, Illinois, United States
View Trial Details
Completed

Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT)

NCT03945292

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Research Site 5 Birmingham, Alabama, United States
  • Research Site 9 Phoenix, Arizona, United States
  • Research Site 14 La Jolla, California, United States
  • Research Site 17 Los Angeles, California, United States
View all 21 locations
View Trial Details

Related conditions